PULSE OXIMETRY SYSTEM AND TECHNIQUES FOR DERIVING CARDIAC AND BREATHING PARAMETERS FROM EXTRA-THORACIC BLOOD FLOW MEASUREMENTS

• US 20080076992A1
• Filed: 09/20/2007
• Published: 03/27/2008
• Est. Priority Date: 09/21/2006
• Status: Active Grant

• Current Assignee: STARR Life Sciences Corp.
• Original Assignee: STARR Life Sciences Corp.
• Inventors: Ayers, Eric, Hete, Bernard, Starr, Eric
• Granted Patent: US 8,359,079 B2
• Time in Patent Office: Days
• US Class Current: 600/324
• CPC Class Codes: A61B 2503/40 Animals
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7257 using Fourier transforms
• CPC Class Codes: A61B 5/7278 Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence

Abstract

Medical devices and techniques derive breath rate, breath distention, and pulse distention measurements of a subject from a pulse oximeter system coupled to a subject. These parameters, together with the conventional physiologic parameters obtained from a pulse oximeter system, can be used to assist in controlling the ventilation levels and the anesthesia levels of the subject. The development has human applications and particular applications for animal research.

Claims

1. A non-invasive pulse oximetry system comprising:

a light source emitting at least two light signals having distinct wavelengths directed at an appendage of a subject; and

a light receiver mounted adjacent to said appendage and which receives said light signals;

wherein the pulse oximetry system derives at least a heart rate value, a blood oxygenation value and a breath distention value from said received light signals.

2. The non-invasive pulse oximetry system of claim 1 wherein the system derives a breath rate that is calculated by filtering the received signals to remove the heart rate component thereof, then reconstructing a breath signal in the absence of the heart rate components and wherein the breath rate is calculated using the breath signal.

3. The non-invasive pulse oximetry system of claim 2 wherein the breath components of the received signals are filtered prior to reconstructing the breath signal.

4. The non-invasive pulse oximetry system of claim 1 wherein the system calculates arterial pulse distention measurements.

5. A non-invasive pulse oximetry system comprising:

A light source adapted to be attached to an external appendage of a subject and configured to emit at least two distinct wavelengths of light directed at the appendage; and

A receiver adapted to be attached to the external appendage of a subject and configured to receive the light from the light source that has been directed at the appendage and generating received signals there from, wherein the pulse oximetry system derives a breath rate of the subject from the received signals, wherein the breath rate is calculated by filtering the received signals to remove heart rate components thereof, then reconstructing a breath signal in the absence of the heart rate components and wherein the breath rate is calculated using the reconstructed breath signal.

6. The non-invasive pulse oximetry system of claim 5 wherein the breath components of the received signals are filtered prior to reconstructing the breath signal.

7. The non-invasive pulse oximetry system of claim 6 wherein the system calculates arterial pulse distention measurements.

8. The non-invasive pulse oximetry system of claim 5 wherein the system calculates arterial pulse distention measurements.

9. A non-invasive pulse oximetry system for a small mammal comprising:

A light source adapted to be attached to an external appendage of a small mammal and configured to emit at least two distinct wavelengths of light directed at the appendage; and

A receiver adapted to be attached to the external appendage of a subject small mammal and configured to receive the light from the light source that has been directed at the appendage and generating received signals there from, wherein the pulse oximetry system derives a breath rate of the subject from the received signals.

10. The non-invasive pulse oximetry system of claim 9 wherein the system is mounted to the tail of a subject animal.

11. The non-invasive pulse oximetry system of claim 10 wherein the breath rate is calculated by filtering the received signals to remove the heart rate component thereof, then reconstructing a breath signal in the absence of the heart rate components and wherein the breath rate is calculated using the breath signal.

12. The non-invasive pulse oximetry system of claim 11 wherein the breath components of the received signals are filtered prior to reconstructing the breath signal.

14. The non-invasive sensor system of claim 11 wherein the system calculates arterial breath distention measurements of the subject.

13. A non-invasive pulse oximetry system comprising:

A light source adapted to be attached to an external appendage of a subject and configured to emit at least two distinct wavelengths of light directed at the appendage; and

A receiver adapted to be attached to the external appendage of a subject and configured to receive the light from the light source that has been directed at the appendage and generating received signals there from, wherein the pulse oximetry system derives at least one physiologic parameter of the subject from the received signals by performing an FFT on at least one time domain signal to generate a frequency domain representation of the at least one time domain signal, filtering the transformed time domain signal in the frequency domain, performing an inverse FFT on the filtered FFT signal to form a filtered time domain signal, and calculating the at least one physiologic parameter by measuring the filtered time domain signal.

15. The non-invasive pulse oximetry system of claim 13 wherein the sensor further derives a breath rate of the subject by reconstructing a breath signal in the absence of heart rate components and wherein the breath rate is calculated using the breath signal.

16. The non-invasive pulse oximetry system of claim 15 wherein the sensor further derives a heart rate of the subject by reconstructing a heart signal in the absence of breath components and wherein the heart rate is calculated using the heart signal.