Respiratory Volume/Flow Gating, Monitoring, and Spirometry System for Mri

• US 20080077038A1
• Filed: 10/31/2005
• Published: 03/27/2008
• Est. Priority Date: 11/02/2004
• Status: Abandoned Application

• Current Assignee: Children's Hospital of Philadelphia (Children's Hospital of Philadelphia Foundation)
• Original Assignee: Children's Hospital of Philadelphia (Children's Hospital of Philadelphia Foundation)
• Inventors: McDonough, Joseph, Arens, Raanan, Sin, Sanghun
• Application Number:
  US11/666,976
• Publication Number:
  US 20080077038A1
• Time in Patent Office: Days
• US Class Current: 600/538
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 5/0873 using optical means
• CPC Class Codes: A61B 5/7285 for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal A61B6/5205, A61B6/541, A61B8/5207, A61B8/543 take precedence
• CPC Class Codes: A61B 6/541 involving acquisition triggered by a physiological signal
• CPC Class Codes: G01R 33/5673 Gating or triggering based on a physiological signal other than an MR signal, e.g. ECG gating or motion monitoring using optical systems for monitoring the motion of a fiducial marker

Abstract

A respiratory volume/flow monitoring system, including a pneumotach that measures micromovements of a membrane in a MRI environment, gates (triggers) a MRI machine to start image acquisition at specific lung volumes or airflow rates during the breathing cycle or other breathing maneuvers of a patient. The system provides breathing motion artifact suppression for any imaging test susceptible to breathing motion artifact, allows respiratory monitoring of the subject during an MRI procedure, and provides the capability to perform spirometric testing while the subject is in the MRI environment. Embodiments of the invention are also applicable for patients undergoing CT imaging or any other imaging modality that allows external triggering.

Claims

1. A respiratory volume/flow monitoring system, comprising:

a pneumotach including a housing, at least one pair of optical fibers including a first fiber and a second fiber, each having an input end portion and an output end portion, the input end portion of said first fiber being connectable to a source of light and the output end portion of said second fiber being connectable to a light intensity measuring unit;

a sensor head, including said input end portion of said second optical fiber and said output end portion of said first optical fiber affixedly located at least in proximity to each other;

a membrane that reflects light emerging from the output end portion of said first fiber to said input end portion of said second optical fiber, said second optical fiber measuring the reflected light as a light measurement and forwarding the light measurement via a fiber optic cable to an electric box; and

an airway coupler communicating air having an air pressure to said pneumotach.

2. The system of claim 1, further comprising a control system configured sample an analog voltage proportional to the light measurement, convert the analog voltage to a volume, display and store waveforms associated with the volume and calculate respirator parameters in real time.

3. The system of claim 2, wherein said control system includes an analog to digital (A/D) board and said control system gating triggers to volume or flow levels based on user input and provides a gating trigger signal to a magnetic resonance imaging (MRI) machine via a digital output channel from the A/D board, through a cable, to a gating input port of the MRI machine.

4. The system of claim 3, wherein said control system is configured to perform processing to at least one of minimize flow levels, adjust for a volume drift, reset a volume baseline, set pre trigger and post trigger delays for compensation to MR sequences, set monitoring alarms, or calculate spirometric parameters.

5. The system of claim 1, further comprising a mask and a pressure guide communicating said mask with said pneumotach.

6. The system of claim 1, said pneumotach further including a first pressure zone defined by said membrane and a first port, said first port including a first syringe tip.

7. The system of claim 6, said pneumotach further including a second pressure zone defined by said membrane and a second port, said second port including a second syringe tip.

8. The system of claim 1, said pneumotach further comprising a pressure sense chamber communicating with said airway coupler.

9. A system for monitoring a respiratory parameter including at least one of respiratory volume or respiratory flow, the system comprising:

a sensor for remotely detecting respiratory air having an air pressure, the sensor comprising;

a pressure chamber configured to remotely receive the respiratory air,

a membrane in the pressure chamber, the membrane movable responsive to the received air in the pressure chamber, and

an optical system configured to optically detect movement of the membrane and to optically transmit the detected movement; and

an electro-optic system for receiving the detected movement and converting the detected movement to an electrical movement measurement signal,

wherein the respiratory parameter is determined based on the movement measurement signal.

10. The system according to claim 9, further comprising:

a mask configured to receive the respiratory air from a patient; and

a pressure guide configured to transfer the respiratory air from the mask to the sensor.

11. The system according to claim 9, wherein the sensor includes a first port configured to communicate the respiratory air to the pressure chamber and a second port configured to communicate further air to the sensor.

12. The system according to claim 9, further comprising a control system for receiving the electrical movement measurement signal and determining the respiration parameter based on the electrical movement measurement signal.

13. The system according to claim 12, wherein the control system is configured to at least one of display waveforms associated with the determined respiration parameter, store the waveforms or calculate respirator parameters based on the electrical movement measurement signal.

14. The system according to claim 12, wherein the control system is configured to generate a gating trigger signal based on the determined respiration parameter and gating triggers set according to volume levels or flow levels, the control system providing the gating trigger signal to a magnetic resonance imaging (MRI) machine.

15. The system according to claim 9, wherein the optical system comprises at least one pair of optical fibers, one end of each of the at least one pair of fibers being arranged in proximity to the membrane, the at least one pair of optical fibers configured to transmit light from a light source to the membrane and detect light reflected from the membrane as the detected movement.

16. The system according to claim 15, wherein the electro-optic system includes the light source and a photodetector, the electro-optic system providing the light to the at least one pair of optical fibers and receiving the detected light from the at least one pair of optical fibers by the photodetector, the photodetector converting the detected light to the electrical movement measurement signal.

17. The system according to claim 15, wherein the pressure chamber includes first and second pressure chambers, the membrane includes first and second membranes in the respective first and second pressure chambers, and the at least one pair of fibers includes two pairs of fibers arranged in proximity to the respective first and second membranes.

18. The system according to claim 17, wherein the sensor includes a first port configured to communicate the respiratory air to the first pressure chamber, and a second port configured to communicate further air to the second pressure chamber.

19. A method for monitoring a respiratory parameter including at least one of respiratory volume or respiratory flow, the method comprising:

remotely receiving respiratory air having an air pressure in a pressure chamber including a membrane, the membrane moving responsive to the received air;

optically detecting movement of the membrane according to light reflected by the membrane;

optically transmitting the optically detected movement to a remote location;

receiving and converting the optically detected movement to an electrical movement measurement signal at the remote location; and

determining the respiratory parameter based on the electrical movement measurement signal.

20. The method according to claim 19, wherein the step of optically detecting the movement includes:

transmitting light from a light source to the membrane via a first optical fiber having an end arranged in proximity to the membrane; and

receiving the reflected light by a second optical fiber having an end arranged in proximity to the membrane.

21. The method according to claim 19, further including the steps of:

remotely receiving further air having a further air pressure in a further air pressure chamber including a further membrane, the further membrane moving responsive to the further air;

repeating the steps of optically detecting, optically transmitting, receiving and converting for movement of the further membrane in order to convert optically detected movement of the further membrane to a further electrical movement measurement signal; and

measuring a pressure difference between the air pressure and the further air pressure from the electrical movement measurement signal and the further electrical movement measurement signal.

22. The method according to claim 19, further including the step of:

remotely receiving further air having a further air pressure, the received further air being coupled to the received air in the pressure chamber in order to adjust for a pressure difference between the air pressure and the further air pressure.

23. The method according to claim 19, further including at least one of displaying waveforms associated with the determined respiration parameter, storing the waveforms or calculating respirator parameters based on the electrical movement measurement signal.

24. The method according to claim 19, further including:

setting gating triggers according to volume levels or flow levels;

generating a gating trigger signal based on the determined respiration parameter and the set gating triggers; and

providing the gating trigger signal to a magnetic resonance imaging (MRI) machine.

25. The method according to claim 19, further including processing the determined respiration parameter to at least one of minimize flow levels, adjust for a volume drift, reset a volume baseline, set pre trigger and post trigger delays for compensation to MR sequences, set monitoring alarms, or calculate spirometric parameters.