MODIFIED RELEASE FORMULATIONS OF A BUPROPION SALT
First Claim
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1. A modified release tablet comprising (a) a core comprising (i) bupropion hydrobromide in an amount of from 40% to 99% by weight of the tablet dry weight;
- (ii) binder in an amount of from 0.25% to 25% by weight of the tablet dry weight; and
(iii) lubricant in an amount of from 0.1% to 6% by weight of the tablet dry weight; and
(b) a control-releasing coat substantially surrounding said core.
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Abstract
The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
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Citations
15 Claims
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1. A modified release tablet comprising
(a) a core comprising (i) bupropion hydrobromide in an amount of from 40% to 99% by weight of the tablet dry weight; -
(ii) binder in an amount of from 0.25% to 25% by weight of the tablet dry weight; and
(iii) lubricant in an amount of from 0.1% to 6% by weight of the tablet dry weight; and
(b) a control-releasing coat substantially surrounding said core. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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Specification