Device for tissue reinforcement having microporous and macroporous structures

• US 20080082177A1
• Filed: 09/29/2006
• Published: 04/03/2008
• Est. Priority Date: 09/29/2006
• Status: Abandoned Application

• Current Assignee: Ethicon Incorporated (Johnson & Johnson)
• Original Assignee: Ethicon Incorporated (Johnson & Johnson)
• Inventors: Arnold, Kelly R., Yang, Chunlin, Do, Hiep, Kammerer, Gene W.
• Application Number:
  US11/540,826
• Publication Number:
  US 20080082177A1
• Time in Patent Office: Days
• US Class Current: 623/23.75
• CPC Class Codes: A61F 2/0045 Support slings
• CPC Class Codes: A61L 31/04 Macromolecular materials
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: A61L 31/146 Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence
• CPC Class Codes: C08L 67/04 Polyesters derived from hydroxycarboxylic acids, e.g. lactones C08L67/06 takes precedence

Abstract

A device for tissue reinforcement. The device has a macroporous structure. At least a section of the macroporous structure is coated with a microporous coating. The microporous and macroporous morphologies allow both cell in-growth and tissue integration.

Claims

1. A tissue reinforcement device comprising;

a macroporous structure; and

,

a microporous coating applied to at least a part of the structure.

2. The device of claim 1, wherein the structure comprises a construct selected from the group consisting of woven, knitted, warped knitted, non-woven, and braided.

3. The device of claim 1, wherein the macroporous structure comprises a material that is not biodegradable.

4. The device of claim 3, wherein the material is selected from the group consisting of cotton, linen, silk, polyamides, polyester fluoropolymers and polyolefins.

5. The device of claim 1, wherein the macroporous material comprises a biodegradable material.

6. The device of claim 5, wherein the biodegradable material comprises a material selected from the group consisting of polymers, copolymers and glasses.

7. The device of claim 1, wherein the coating comprises a biodegradable foam.

8. The device of claim 1, wherein the foam comprises a polymer selected from the group consisting of polymers and copolymers.

9. The device of claim 8, wherein the polymer is selected from the group consisting of polylactic acid, polyglycolic acid, polycaprolactone, polydioxanone, trimethylene carbonate, and polyvinyl alcohol.

10. The device of claim 1, additionally comprising a bioactive agent.

11. The device of claim 10, wherein the bioactive agent additionally comprises a bioactive agent selected from the group consisting of antimicrobial agents, antibiotics, anti-inflammatory agents, oxidized regenerated cellulose, hyaluronic acid, and immunosuppressants.

12. A method of treating a tissue injury, the method comprising:

providing a tissue reinforcement device comprising;

a macroporous structure; and

,

a microporous coating applied to at least a part of the structure;

accessing the site of the damaged tissue,

preparing the site for implant placement,

placing the tissue treatment device in a section of damaged tissue, and,

securing the device to the site.

13. The method of claim 12, where the tissue injury is herniation or damage to the pelvic floor.

14. The method of claim 13, wherein the herniation is selected from the group consisting of abdominal hernias, inguinal hernias, femoral hernias, umbilical hernias, and incisional hernias.