System and method for continuous detection of an analyte in bloodstream
First Claim
1. A method for performing a tissue assay, comprising the steps of:
- positioning a biosensor in fluid communication with tissue of the patient whereby the tissue contacts the biosensor, the biosensor having at least one material adapted to bind to an analyte;
detecting a change in at least one of an electrical and mechanical property of the biosensor indicative of a mass change resulting from binding of the at least one material with the analyte; and
transmitting a real time signal representative of a mass change to a display module to provide real time analysis by a clinician.
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Accused Products
Abstract
A method for performing a blood assay is disclosed. The method includes the steps of: positioning an acoustic biosensor in fluid communication with a blood vessel of the patient whereby blood from the blood vessel contacts the biosensor. The biosensor includes at least one material adapted to bind to an analyte. The method also includes the steps of detecting a change in at least one of an electrical and mechanical property of the biosensor indicative of a mass change resulting from binding of the at least one material with the analyte and transmitting a real time signal representative of mass change to a display module to provide real time analysis by a clinician.
29 Citations
25 Claims
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1. A method for performing a tissue assay, comprising the steps of:
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positioning a biosensor in fluid communication with tissue of the patient whereby the tissue contacts the biosensor, the biosensor having at least one material adapted to bind to an analyte; detecting a change in at least one of an electrical and mechanical property of the biosensor indicative of a mass change resulting from binding of the at least one material with the analyte; and transmitting a real time signal representative of a mass change to a display module to provide real time analysis by a clinician.
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2. A method for performing a blood assay, comprising the steps of:
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positioning an acoustic biosensor in fluid communication with a blood vessel of the patient whereby blood from the blood vessel contacts the biosensor, the biosensor having at least one material adapted to bind to an analyte; detecting a change in at least one of an electrical and mechanical property of the biosensor indicative of a mass change resulting from binding of the at least one material with the analyte; and transmitting a real time signal representative of a mass change to a display module to provide real time analysis by a clinician. - View Dependent Claims (3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A medical analyzer to assay blood for an analyte, which comprises:
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an acoustic biosensor adapted to be in fluid communication with a blood vessel whereby blood from the blood vessel contacts the biosensor, the biosensor having at least one material adapted to bind to an analyte of the blood; an oscillator for generating a mechanical wave form in the biosensor; and a detector adapted to detect a change in resonant frequency of the mechanical wave form indicative of a mass change resulting from the binding of the at least one material of the biosensor with the analyte of the blood and to generate a real time signal representative of the mass change of the biosensor to provide real time analysis by a clinician. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22)
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23. A medical analyzer to assay blood for an analyte, which comprises:
an acoustic biosensor adapted to be in fluid communication with a blood vessel whereby blood from the blood vessel contacts the biosensor, the biosensor having at least one material adapted to bind to an analyte of the blood, the biosensor being adapted to transmit a mass change resulting from the binding of the at least one material of the biosensor with the analyte of the blood in response to a change in at least one of an electrical and mechanical property of the biosensor. - View Dependent Claims (24, 25)
Specification