DEVICES FOR REDUCTION OF POST OPERATIVE ILEUS

• US 20080086078A1
• Filed: 09/18/2007
• Published: 04/10/2008
• Est. Priority Date: 10/06/2006
• Status: Abandoned Application

• Current Assignee: Ethicon Endo-Surgery, Inc. (Johnson & Johnson)
• Original Assignee: Ethicon Endo-Surgery, Inc. (Johnson & Johnson)
• Inventors: Pomeroy, Mark, Murray, Michael A., Powell, Darrel M., Shurtleff, Carl J.
• Application Number:
  US11/856,773
• Publication Number:
  US 20080086078A1
• Time in Patent Office: Days
• US Class Current: 604/58
• CPC Class Codes: A61B 17/072 for applying a row of staples in a single action , e.g. the staples being applied simultaneously
• CPC Class Codes: A61B 17/07292 Reinforcements for staple line, e.g. pledgets
• CPC Class Codes: A61B 17/115 Staplers for performing anastomosis in a single operation
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective

Abstract

An apparatus and method for reducing post-operative ileus and/or gastric stasis is described. The method can include applying to the intestine a therapeutically effective amount of a composition comprising a drug that is effective in reducing post-operative ileus and/or gastric stasis, such as by introducing the composition through a surgical access device, such as a trocar or endoscope. The apparatus can include a surgical fastener and a buttress comprising the composition.

Claims

1. A surgical fastening apparatus comprising:

at least one surgical fastener; and

a therapeutically effective amount of a composition effective in reducing post operative ileus.

2. The apparatus of claim 1 wherein the device comprises at least one surgical staple.

3. The apparatus of claim 1 comprising a buttress.

4. The apparatus of claim 3 wherein the composition is operatively associated with the buttress.

5. The apparatus of claim 3 wherein the buttress is formed from a bioabsorbable material.

6. The apparatus of claim 1 wherein the surgical fastening apparatus is a surgical stapler.

7. The apparatus of claim 6 wherein the stapler is a linear stapler.

8. The apparatus of claim 6 wherein the stapler is a circular stapler.

9. The apparatus of claim 8 wherein the circular stapler comprises a stapler body, an anvil head removably attached to stapler body, a first buttress associated with the stapler body;

and a second buttress associated with the anvil head; and

wherein at least one of the buttresses comprises the composition effective in reducing post operative ileus.

10. An apparatus for use in reducing post-operative ileus, the apparatus comprising:

a drug effective to reduce post-operative ileus, and

a device for applying the drug, wherein the device is sized and shaped to be introduced through a surgical access device, and wherein the device provides for selective application of the drug.

11. The apparatus of claim 10 wherein the device comprises a sheet having at least one opening, and wherein the drug is disposed on the sheet, such that the sheet can be applied to an interior portion of the body without the drug contacting a selected area of the body.

12. The apparatus of claim 10 including a sprayable powder comprising the drug.

13. The apparatus of claim 12 wherein the sprayable powder comprises ORC.

14. The apparatus of claim 10 wherein the device comprises a roll-on applicator.

15. The apparatus of claim 10 wherein the drug is selected from the group consisting of a non-steroidal anti-inflammatory drug, galantamine, and a mast cell degranulation inhibitor.

16. The apparatus of claim 10 including a gel comprising the drug.