OPTICAL LENS SYSTEM AND METHOD FOR MICROFLUIDIC DEVICES
First Claim
1. An apparatus for imaging one or more selected fluorescence indications from a microfluidic device including an array of closed reaction chambers, the apparatus comprising:
- an imaging path coupled to the array of closed reaction chambers in the microfluidic device, the imaging path providing for transmission of one or more fluorescent emission signals derived from one or more samples in the array of closed reaction chambers in the microfluidic device, each of the closed reaction chambers in the array of closed reaction chambers having a chamber size, the chamber size being characterized by an actual spatial dimension normal to the imaging path; and
an optical lens system coupled to the imaging path, the optical lens system being adapted to transmit the one or more fluorescent signals derived from the one or more samples in the array of closed reaction chambers in the microfluidic device, wherein the optical lens system is adapted to reduce a size of the actual spatial dimension to a reduced size less than the size of the actual spatial dimension.
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Accused Products
Abstract
An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic device. The imaging path provides for transmission of one or more fluorescent emission signals derived from one or more samples in the at least one chamber of the at least one microfluidic device. The chamber has a chamber size, the chamber size being characterized by an actual spatial dimension normal to the imaging path. The apparatus also includes an optical lens system coupled to the imaging path. The optical lens system is adapted to transmit the one or more fluorescent signals associated with the chamber.
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Citations
20 Claims
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1. An apparatus for imaging one or more selected fluorescence indications from a microfluidic device including an array of closed reaction chambers, the apparatus comprising:
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an imaging path coupled to the array of closed reaction chambers in the microfluidic device, the imaging path providing for transmission of one or more fluorescent emission signals derived from one or more samples in the array of closed reaction chambers in the microfluidic device, each of the closed reaction chambers in the array of closed reaction chambers having a chamber size, the chamber size being characterized by an actual spatial dimension normal to the imaging path; and
an optical lens system coupled to the imaging path, the optical lens system being adapted to transmit the one or more fluorescent signals derived from the one or more samples in the array of closed reaction chambers in the microfluidic device, wherein the optical lens system is adapted to reduce a size of the actual spatial dimension to a reduced size less than the size of the actual spatial dimension. - View Dependent Claims (2, 3, 4, 5, 6)
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7. An apparatus for imaging a microfluidic device comprising a plurality of processing sites, the apparatus comprising:
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an illumination system coupled to the microfluidic device and adapted to illuminate the microfluidic device with electromagnetic radiation, wherein the microfluidic device is characterized by a device dimension including the plurality of processing sites;
an imaging system coupled to the microfluidic device and adapted to simultaneously receive electromagnetic radiation emitted from the plurality of processing sites; and
a detector coupled to the imaging system and characterized by a detection area less than the device dimension. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification