IMPLANTABLE VALVE PROSTHESIS

• US 20080091261A1
• Filed: 10/15/2007
• Published: 04/17/2008
• Est. Priority Date: 10/13/2006
• Status: Abandoned Application

• Current Assignee: Creighton University
• Original Assignee: Creighton University
• Inventors: Long, Andrew, Csordas, Attila
• Application Number:
  US11/872,504
• Publication Number:
  US 20080091261A1
• Time in Patent Office: Days
• US Class Current: 623/1.24
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2475 Venous valves
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0066 stapled
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/0078 hyperboloidal
• CPC Class Codes: A61F 2230/008 paraboloidal

Abstract

An implantable valve prosthesis (10) having a deformable body (12) defining an upstream opening in fluid communication with a downstream opening wherein the deformable body (12) has a first configuration that permits fluid flow in one direction only and a second configuration that prevents retrograde fluid flow in the opposite direction is disclosed.

Claims

1. An implantable valve prosthesis (10) comprising a deformable body (12) having a first configuration that permits fluid flow communication in one direction while a second configuration prevents fluid communication in an opposite direction. The deformable body (12) defines a generally cylindrical configuration with a downstream opening in communication with an opposing upstream opening such that when the deformable body (12) is in the first configuration the downstream opening has substantially the same shape as the upstream opening, and when the deformable body (12) is in the second configuration the downstream opening has a smaller shape than the upstream opening, thereby preventing fluid flow communication in the opposite direction.

2. The implantable valve prosthesis (10) of claim 1, wherein the deformable body (12) is made from two or more membranes.

3. The implantable valve prosthesis (10) of claim 1, wherein the downstream opening (30) in the first configuration is in an open position that permits fluid flow in one direction only and in the second configuration the downstream opening (3) is in a closed position such that retrograde fluid flow through the downstream opening to the upstream opening is prevented in the second configuration.

4. The implantable valve prosthesis (10) of claim 1 wherein the deformable body (12) is bowed outwardly in the second configuration.

5. The implantable valve prosthesis (10) of claim 1, wherein the deformable body (12) is adapted to engage a stent for retaining the prosthesis (10) inside the lumen of a vessel.

6. The implantable valve prosthesis (10) of claim 1, wherein the deformable body (12) defines a scalloped opening.

7. The implantable valve prosthesis (10) of claim 1, wherein the deformable body (12) defines opposing slots along the downstream opening (30).

8. The implantable valve prosthesis (10) of claim 1, wherein the deformable body (12) is retained inside the lumen of a vessel using by use of an adhesive.

9. The implantable valve prosthesis (10) of claim 1, wherein the deformable body (12) is adapted to be engaged to a catheter (40) for insertion into the lumen of a vessel.

10. The implantable valve prosthesis (10) of claim 1, wherein the deformable body (12) has a conical configuration.

11. The implantable valve prosthesis (10) of claim 1, wherein the deformable body (12) has a cylindrical configuration.

12. The implantable valve prosthesis (10) of claim 1, wherein the deformable body (12) includes one or more expandable balloons (41, 42).

13. An implantable valve prosthesis (10) may include a deformable body (12) having a first position for permitting fluid flow communication inside a lumen in one direction only and a second position for preventing fluid flow communication inside the lumen in the opposite direction, the deformable body (12) being adapted to engage an expandable stent.

14. A method for deploying an implantable valve prosthesis (10) may include the steps of:

providing a catheter (40) defining a proximal end and a distal end;

attaching the distal end of the catheter (40) to an implantable valve prosthesis (10) having a deformable body (12) having a first configuration that permits fluid flow communication in one direction while a second configuration prevents fluid communication in an opposite direction with the deformable body (12) defining a generally cylindrical configuration with a downstream opening in communication with an opposing upstream opening such that when the deformable body (12) is in the first configuration the downstream opening has substantially the same shape as the upstream opening, and when the deformable body (12) is in the second configuration the downstream opening has a smaller shape than the upstream opening, thereby preventing fluid flow communication in the opposite direction; and

implanting the distal end of the catheter (40) inside the lumen of a body such that the implantable valve prosthesis (10) is disposed across the lumen of the body in a manner that permits selective fluid flow communication through the lumen by the deformable body of the implantable valve prosthesis (10).