SURGICAL PROSTHESIS HAVING BIODEGRADABLE AND NONBIODEGRADABLE REGIONS
First Claim
1. A composite prosthesis, comprising:
- a coated mesh having at least one opening through a first surface and a second surface of the coated mesh;
the coated mesh comprising a mesh and a biocompatible coating substantially covering the mesh; and
a barrier material comprising a biocompatible membrane constructed and arranged to cover at least one surface of the coated mesh.
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Accused Products
Abstract
A prosthesis for repairing a hernia includes an adhesion-resistant biodegradable region and an opposing tissue-ingrowth biodegradable region. When the prosthesis is implanted into the patient, the adhesion-resistant biodegradable region covers a fascial defect of the hernia, and the tissue-ingrowth biodegradable region is located above the adhesion-resistant biodegradable region while being exposed substantially only to the host'"'"'s subcutaneous tissue layer. This orientation allows the tissue-ingrowth biodegradable region to become firmly incorporated with the host'"'"'s body tissue. The adhesion-resistant biodegradable region faces the internal organs and decreases the incidence of adhesions and/or bowel obstruction.
122 Citations
16 Claims
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1. A composite prosthesis, comprising:
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a coated mesh having at least one opening through a first surface and a second surface of the coated mesh;
the coated mesh comprising a mesh and a biocompatible coating substantially covering the mesh; and
a barrier material comprising a biocompatible membrane constructed and arranged to cover at least one surface of the coated mesh. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method for limiting the incidence of postoperative adhesions arising from a repair of a defect in a tissue, wherein the tissue defect is located near a region of potential postoperative adhesion, the method comprising the steps of:
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providing a composite prosthesis comprising;
a coated mesh having at least one opening through a first surface and a second surface of the coated mesh;
the coated mesh comprising a mesh and a biocompatible coating substantially covering the mesh; and
a barrier material comprising a biocompatible membrane constructed and arranged to cover at least one surface of the coated mesh and to isolate the repaired defect; and
positioning the composite prosthesis to cover the defect whereby the formation of postoperative adhesions is limited. - View Dependent Claims (8, 9, 10, 11, 12)
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13. A method of making a composite prosthesis comprising the steps of:
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coating a mesh with a biocompatible coating to form a coated mesh having at least one opening; and
attaching an adhesion-resistant barrier material to the coated mesh. - View Dependent Claims (14, 15, 16)
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Specification