PHOSPHONATE COMPOUNDS
First Claim
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1. A compound comprising a phosphonate ester formed by a covalent linking of tenofovir to an alkylpropanediol, or a pharmaceutically acceptable salt thereof.
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Abstract
The present invention relates to phosphonate compounds, compositions containing them, processes for obtaining them, and their use for treating a variety of medical disorders, e.g., osteoporosis and other disorders of bone metabolism, cancer, viral infections, and the like.
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17 Claims
- 1. A compound comprising a phosphonate ester formed by a covalent linking of tenofovir to an alkylpropanediol, or a pharmaceutically acceptable salt thereof.
- 5. A method for the treatment of a viral disease selected from human immunodeficiency virus, influenza, herpes simplex virus, human herpes virus, cytomegalovirus, hepatitis B and C virus, Epstein-Barr virus, varicella zoster virus, orthopox virus, ebola virus and papilloma virus comprising administering an effective amount of a compound optionally in a pharmaceutically acceptable carrier, wherein the compound comprises a phosphonate ester formed by a covalent linking of tenofovir to an alkylpropanediol, or a pharmaceutically acceptable salt thereof.
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