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Induction of and Maintenance of Nucleic Acid Damage in Pathogens Using Riboflavin and Light

  • US 20080107636A1
  • Filed: 10/31/2007
  • Published: 05/08/2008
  • Est. Priority Date: 06/02/2000
  • Status: Active Grant
First Claim
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1. A process for inactivating white blood cells which may be contained in a fluid comprising:

  • adding to the fluid containing white blood cells an effective amount of riboflavin;

    exposing the fluid and riboflavin to light of an appropriate wavelength to activate the riboflavin and cause damage to the nucleic acid of the white blood cells; and

    substantially maintaining the damage to the nucleic acids of the white blood cells to prevent re-activation of the white blood cells.

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