Initiator Coating of Staples

• US 20080110961A1
• Filed: 11/10/2006
• Published: 05/15/2008
• Est. Priority Date: 11/10/2006
• Status: Abandoned Application

• Current Assignee: Ethicon Endo-Surgery, Inc. (Johnson & Johnson)
• Original Assignee: Ethicon Endo-Surgery, Inc. (Johnson & Johnson)
• Inventors: Eichmann, Stephen E., Ortiz, Mark S., Voegele, James W., Shelton, Frederick E.
• Application Number:
  US11/558,497
• Publication Number:
  US 20080110961A1
• Time in Patent Office: Days
• US Class Current: 227/179.1
• CPC Class Codes: A61B 17/0644 penetrating the tissue, deformable to closed position
• CPC Class Codes: A61B 17/07207 the staples being applied sequentially
• CPC Class Codes: A61B 17/115 Staplers for performing anastomosis in a single operation
• CPC Class Codes: A61B 2017/00495 for two-component glue
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective

Abstract

Provided are surgical fasteners coated with a material including an initiator configured for activation upon application of an initiator. The surgical fasteners may be configured for use in combination with a surgical fastener applying apparatus. In one version, the surgical fastener is a surgical staple including a pair of legs, a crown interconnecting the pair of legs, and a material including an initiator coating at least a portion of the legs and/or crown. Adhesive may be delivered into contact with the initiator associated with the surgical fasteners such that a desirable size, shape, and configuration of activated or polymerized adhesive is created.

Claims

1. A method for fastening tissue comprising the steps of:

providing a stapling instrument comprising a handle, a first and a second opposed tissue clamping member connected to the handle, the first and the second opposed tissue clamping members movable between an open position for receiving tissue and a closed position for stapling tissue therebetween, the first clamping member including a plurality of staples disposed therein in an array, the second clamping member comprising an anvil for forming the staples;

providing each of the plurality of staples with a portion of biocompatable material containing an adhesive initiator;

providing an adhesive applicator operably configured to deliver a portion of biocompatable material containing a fluid adhesive that is inactive, where the fluid adhesive is operably configured for activation by the adhesive initiator upon contact;

applying the plurality of staples to tissue;

providing the fluid adhesive in the region of the plurality of staples in an indiscriminate manner;

activating the fluid adhesive in regions adjacent the plurality of staples in which the fluid adhesive is associated with the adhesive initiator.

2. The method of claim 1, wherein the fluid adhesive and the adhesive initiator are bioabsorbable.

3. The method of claim 1, wherein the plurality of staples are bioabsorbable.

4. The method of claim 1, wherein the adhesive is selected from the group consisting of a polymerizable monomer, a polymerizable 1,1,1,1-disubstituted ethylene monomer, a cyanoacrylate formulation, and combinations thereof.

5. The method of claim 1, wherein the fluid adhesive is configured in a concentration such that isolated regions of activated adhesive are formed adjacent each of a plurality of the staples.

6. The method of claim 1, wherein the adhesive is configured in a concentration such that regions of activated adhesive are formed adjacent a plurality of the staples.

7. The method of claim 1, further comprising the step of washing away inactive fluid adhesive from the tissue.

8. The method of claim 1, wherein the fluid adhesive is configured for initiation at about a crown and at about a first leg and a second leg of each of the plurality of surgical staples.

9. The method of claim 1, wherein the step of providing the fluid adhesive further comprises applying the fluid adhesive to an external surface of tissue and to an internal surface of tissue.

18. The method of claim 1, wherein the step of providing the adhesive initiator further comprises applying the adhesive initiator to an external surface of the tissue and to an internal surface of the tissue.

10. A method for fastening tissue comprising the steps of:

providing a stapling instrument comprising a handle, first and a second opposed tissue clamping members connected to the handle, the first and a second opposed tissue clamping members movable between an open position for receiving tissue and a closed position for stapling tissue therebetween, the first clamping member including a plurality of staples disposed therein in an array, the second clamping member comprising an anvil for forming the staples;

providing a staple having a portion of biocompatable material containing an inactive adhesive;

providing an initiator applicator operably configured to deliver a portion of biocompatable material containing an adhesive initiator, wherein the adhesive initiator is operably configured to activate the adhesive;

applying the plurality of staples to tissue;

providing the adhesive initiator in the region of the plurality of staples in an indiscriminate manner;

activating the adhesive in regions adjacent the plurality of staples in which the adhesive is associated with the adhesive initiator.

11. The method of claim 10, wherein the adhesive and the adhesive initiator are bioabsorbable.

12. The method of claim 10, wherein the staples are bioabsorbable.

13. The method of claim 10, wherein the adhesive is selected from the group consisting of a polymerizable monomer, a polymerizable 1,1,1,1-disubstituted ethylene monomer, a cyanoacrylate formulation, and combinations thereof.

14. The method of claim 10, wherein the initiator is configured in a concentration such that isolated regions of activated adhesive are formed adjacent each of a plurality of the staples.

15. The method of claim 10, wherein the adhesive and the adhesive initiator are configured in a concentration such that regions of activated adhesive are formed adjacent at least two of the plurality of staples.

16. The method of claim 10, further comprising the step of washing away inactive fluid adhesive from the tissue.

17. The method of claim 10, wherein the adhesive is configured for initiation at about a crown and at about a first leg and a second leg of each of the plurality of surgical staples.