USE OF DIPYRIDAMOLE OR MOPIDAMOL FOR TREATMENT AND PREVENTION OF FIBRIN-DEPENDENT MICROCIRCULATION DISORDERS
First Claim
1. A method for treating or preventing in a mammal fibrin-dependent microcirculation disorders or disease states where such microcirculation disorders are involved comprising administering to said mammal an effective amount of a pharmaceutical composition comprising a pyrimido-pyrimidine selected from dipyridamole, mopidamol, and the pharmaceutically acceptable salts thereof alone in a monopreparation.
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Abstract
A method of treatment of the human or non-human animal body for treating fibrin-dependent microcirculation disorders is disclosed, for example, microcirculation disorders caused by metabolic diseases, inflammatory reactions or autoimmune diseases; peripheral microcirculation disorders or microcirculation disorders associated with increased cell fragmentation comprising administering to a human or non-human animal body in need of such treatment an effective amount of a pharmaceutical composition containing a pyrimido-pyrimidine selected from dipyridamole, mopidamol and the pharmaceutically acceptable salts thereof, and the use of said pyrimido-pyrimidine for the manufacture of a corresponding pharmaceutical composition.
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Citations
15 Claims
- 1. A method for treating or preventing in a mammal fibrin-dependent microcirculation disorders or disease states where such microcirculation disorders are involved comprising administering to said mammal an effective amount of a pharmaceutical composition comprising a pyrimido-pyrimidine selected from dipyridamole, mopidamol, and the pharmaceutically acceptable salts thereof alone in a monopreparation.
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2. A method for treating in a mammal fibrin-dependent microcirculation disorders or disease states where such microcirculation disorders are involved comprising administering to said mammal an effective amount of a pharmaceutical composition comprising a pyrimido-pyrimidine selected from dipyridamole, mopidamol, and the pharmaceutically acceptable salts thereof in combination with an agent selected from the group consisting of:
- acetylsalicylic acid (ASA), clopidogrel, ticlopidine and the pharmaceutically acceptable salts thereof, fibrinogen receptor antagonists, heparin, heparinoids, antithrombins, ACE inhibitors, Angiotensin II antagonists, calcium-antagonists and lipid-lowering agents;
wherein ASA is administered orally in a daily dosage of 10 to 30 mg. - View Dependent Claims (3, 4, 5, 13)
- acetylsalicylic acid (ASA), clopidogrel, ticlopidine and the pharmaceutically acceptable salts thereof, fibrinogen receptor antagonists, heparin, heparinoids, antithrombins, ACE inhibitors, Angiotensin II antagonists, calcium-antagonists and lipid-lowering agents;
Specification