Cardiac resynchronization therapy optimization using cardiac activation sequence information
First Claim
1. A method of pacing a heart to produce a fusion response, comprising:
- obtaining a cardiac signal vector associated with all or a portion of one or more cardiac activation sequences;
adjusting one or more pacing parameters and monitoring the cardiac signal vector during pacing parameter adjustment;
detecting a change in a characteristic of the cardiac signal vector in response to the one or more adjusted pacing parameters, the change indicative of a cardiac fusion response; and
delivering a pacing therapy to produce the cardiac fusion response using the one or more adjusted pacing parameters.
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Abstract
Systems and methods provide for pacing a heart to improve pumping efficiency of the heart, such as by producing a cardiac fusion response for patient'"'"'s subject to cardiac resynchronization therapy. A pacing parameter, such as an A-V delay, V-V delay, lead/electrode configuration or vector, is adjusted and a cardiac signal vector representative of all or a portion of one or more cardiac activation sequences is monitored during pacing parameter adjustment. A change in a characteristic of the cardiac signal vector is detected in response to an adjusted pacing parameter, the change indicative of a cardiac fusion response. A pacing therapy may be delivered to produce the cardiac fusion response using the adjusted pacing parameter.
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Citations
25 Claims
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1. A method of pacing a heart to produce a fusion response, comprising:
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obtaining a cardiac signal vector associated with all or a portion of one or more cardiac activation sequences; adjusting one or more pacing parameters and monitoring the cardiac signal vector during pacing parameter adjustment; detecting a change in a characteristic of the cardiac signal vector in response to the one or more adjusted pacing parameters, the change indicative of a cardiac fusion response; and delivering a pacing therapy to produce the cardiac fusion response using the one or more adjusted pacing parameters. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A system, comprising:
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a plurality of electrodes configured for at least sensing cardiac electrical activity and energy delivery; a signal processor coupled to the electrodes and configured to produce a cardiac signal vector associated with all or a portion of one or more cardiac activation sequences; and a controller coupled to the electrodes and the signal processor, the controller configured to adjust a pacing parameter and detect a change in a characteristic of the cardiac signal vector in response to an adjusted pacing parameter, the change indicative of a cardiac fusion response. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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Specification