Annular Ring Implant

• US 20080119947A1
• Filed: 11/16/2007
• Published: 05/22/2008
• Est. Priority Date: 11/18/2006
• Status: Abandoned Application

• Current Assignee: Smith & Nephew Incorporated (Smith & Nephew PLC)
• Original Assignee: Smith & Nephew Incorporated (Smith & Nephew PLC)
• Inventors: Huckle, James, Ali, Saad
• Application Number:
  US11/941,231
• Publication Number:
  US 20080119947A1
• Time in Patent Office: Days
• US Class Current: 623/23.72
• CPC Class Codes: A61F 2/30749 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2/30756 Cartilage endoprostheses A61F2/3603 takes precedence
• CPC Class Codes: A61F 2002/30032 differing in absorbability or resorbability, i.e. in absorption or resorption time
• CPC Class Codes: A61F 2002/30062 (bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
• CPC Class Codes: A61F 2002/302 toroidal, e.g. rings
• CPC Class Codes: A61F 2002/30579 with mechanically expandable devices, e.g. fixation devices
• CPC Class Codes: A61F 2002/30677 Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
• CPC Class Codes: A61F 2002/30751 for attaching cartilage scaffolds to underlying bone
• CPC Class Codes: A61F 2002/30766 Scaffolds for cartilage ingrowth and regeneration
• CPC Class Codes: A61F 2002/3092 having an open-celled or open-pored structure
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2230/0065 toroidal, e.g. ring-shaped, doughnut-shaped
• CPC Class Codes: A61F 2250/003 differing in adsorbability or resorbability, i.e. in adsorption or resorption time
• CPC Class Codes: A61F 2310/00011 Metals or alloys
• CPC Class Codes: A61F 2310/00179 Ceramics or ceramic-like structures
• CPC Class Codes: A61F 2310/00365 Proteins; Polypeptides; Degradation products thereof
• CPC Class Codes: A61L 27/3604 characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
• CPC Class Codes: A61L 27/3641 characterised by the site of application in the body materials for artificial blood vessels A61L27/507; materials for use in artificial skin A61L27/60
• CPC Class Codes: A61L 27/3645 Connective tissue
• CPC Class Codes: A61L 27/3804 characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
• CPC Class Codes: A61L 27/3843 : Connective tissue
• CPC Class Codes: A61L 27/50 : Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials

Abstract

The present disclosure relates to an implant having a substitute tissue structure and an annular anchoring element for anchoring the substitute tissue structure into an annular groove formed in an underlying tissue at or near an implantation site. At least a part of the annular anchoring element is bonded to the substitute tissue structure. A method of tissue repair is also disclosed.

Claims

1. An implant comprising:

a substitute tissue structure; and

an annular anchoring element for anchoring the substitute tissue structure into an annular groove formed in an underlying tissue at or near an implantation site,

wherein at least part of the annular anchoring element is bonded to the substitute tissue structure.

2. The implant of claim 1 wherein the damaged tissue is selected from a group consisting essentially of cartilage, synovium, tendon, ligament, meniscus, and bone.

3. The implant of claim 1 wherein the damaged tissue is cartilage and the annular groove is formed in subchondral bone.

4. The implant of claim 1 wherein the substitute tissue structure includes a material selected from the group consisting essentially of a natural polymer, a synthetic polymer, a ceramic material, a metal, and combinations thereof.

5. The implant of claim 1 wherein at least a part of the substitute tissue structure is resorbable.

6. The implant of claim 1 wherein the substitute tissue structure comprises at least one element selected from a group consisting essentially of an antibiotic, an analgesic, an anti-viral agent, an antimicrobial agent, an anti-inflammatory agent, a growth factor, a hormone, a cytokine, a protein, an osteogenic agent, a chondrogenic agent, a glycosaminoglycan, an immunosuppressant, a nucleic acid, a cell type, a tissue fragment, and combinations thereof.

7. The implant of claim 6 wherein the cell type is selected from a group consisting essentially of an osteocyte, a fibroblast, a stem cell, a pluripotent cell, a chondrocyte progenitor cell, a chondrocyte, an osteoclast, an osteoblast, an endothelial cell, a macrophage, an adipocyte, a monocyte, a plasma cell, a mesenchymal stem cell, an epithelial cell, a myoblast, a tenocyte, a ligament fibroblast, and bone marrow cell type.

8. The implant of claim 7 wherein the tissue fragment is selected from a group consisting essentially of cartilage, meniscus, tendon, ligament, periosteum, and bone.

9. The implant of claim 7 wherein the cell type is selected from a group consisting essentially of an autogenic cell, an allogenic cell, a xenogeneic cell, and combinations thereof.

10. The implant of claim 1 wherein the annular anchoring element includes a material selected from a group consisting essentially of a natural polymer, a synthetic polymer, a gel, a ceramic material, and a metal.

11. The implant of claim 1 wherein the annular anchoring element comprises at least one agent selected from a group consisting essentially of an osteogenic agent, an osteoconductive agent, and an osteoinductive agent.

12. The implant of claim 1 wherein at least part of the annular anchoring element is resorbable.

13. The implant of claim 1 wherein the annular anchoring element is deformable.

14. The implant of claim 1 wherein the annular anchoring element is expandable.

15. The implant of claim 1 wherein the annular anchoring element is provided with an anti-rotational element.

16. The implant of claim 1 wherein the bonding includes chemical bonding.

17. The implant of claim 1 wherein the bonding is achieved using chloroform and a polycaprolactone.

18. The implant of claim 1 wherein the substitute tissue structure includes a diameter that is larger than a diameter of the annular anchoring element.

19. A method of tissue repair comprising:

forming a groove around at least a part of damaged tissue, the groove extending into the underlying tissue below the damaged tissue;

removing the damaged tissue about which the groove extends;

providing an implant comprising a substitute tissue structure having an annular anchoring element bonded thereto; and

inserting the implant into the groove such that the annular anchoring element is located within the groove.

20. The method of claim 19 wherein the damaged tissue is cartilage and the underlying tissue is subchondral bone.