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ANALYSIS OF RARE CELL-ENRICHED SAMPLES

  • US 20080124721A1
  • Filed: 06/13/2007
  • Published: 05/29/2008
  • Est. Priority Date: 06/14/2006
  • Status: Abandoned Application
First Claim
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1. A method for detecting cancer in a subject comprising:

  • enriching a sample from said subject for rare cells by flowing said sample through an array of obstacles coated with antibodies that specifically bind to one or more cell populations in said sample to obtain a rare cell-enriched sample, wherein said rare cells in said sample are in a concentration of less than 1 in 100,000 cells prior to said enrichment, anddetecting the presence or absence of a rare cell nucleic acid in said rare cell-enriched sample, wherein the presence of said rare cell nucleic acid in said rare cell-enriched sample indicates the presence of said cancer in said subject.

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