MASS SPECTROMETRY WITH LASER ABLATION
First Claim
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1. A method for mass spectrometric analysis of surface material comprising:
- (a) vaporizing the surface material at a removal site by pulses of laser light;
(b) dissolving vaporized material in a liquid at an collection site; and
(c) providing the liquid containing dissolved material to an ion source.
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Abstract
A mass spectrometric analysis of surface material is performed by vaporizing the surface material with pulses of laser light and then collecting the vaporized material by dissolving it in a liquid. The liquid with the dissolved material is then fed to an ionization process, preferably an electrospray ionization process. The resulting ions are then analyzed with a mass spectrometer. The method is particularly suited for use with imaging mass spectrometry.
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Citations
10 Claims
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1. A method for mass spectrometric analysis of surface material comprising:
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(a) vaporizing the surface material at a removal site by pulses of laser light; (b) dissolving vaporized material in a liquid at an collection site; and (c) providing the liquid containing dissolved material to an ion source. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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Specification