Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells
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Abstract
A method of manufacturing a tissue matrix for implantation into a patient is disclosed. The method sets forth collecting embryonic stem cells from a placenta which has been treated to remove residual cord blood and seeding the collected stem cells onto or into a tissue matrix. The seeded tissue matrix is then implanted on or into a patient. The seeded tissue matrix made by the method of the present invention is also disclosed.
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Citations
43 Claims
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1-23. -23. (canceled)
- 24. A method of making a tissue matrix, comprising seeding human placental stem cells into or onto a decellularized or synthetic tissue matrix, wherein said stem cells are from a human placenta that has been drained of cord blood and perfused to remove residual blood, and comprise stem cells that are CD34−
- 31. A decellularized or synthetic tissue matrix comprising human placental stem cells that are CD34−
- 39. The tissue matrix of claim 39, wherein said decellularized tissue is non-human.
Specification