SYSTEM AND METHOD FOR AFFECTING GATRIC FUNCTIONS

• US 20080132962A1
• Filed: 12/01/2006
• Published: 06/05/2008
• Est. Priority Date: 12/01/2006
• Status: Abandoned Application

• Current Assignee: Ethicon Incorporated (Johnson & Johnson)
• Original Assignee: Ethicon Incorporated (Johnson & Johnson)
• Inventors: Wahlgren, Stephen B., Tracey, Michael R., DiUbaldi, Anthony
• Application Number:
  US11/565,706
• Publication Number:
  US 20080132962A1
• Time in Patent Office: Days
• US Class Current: 607/2
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control
• CPC Class Codes: A61N 1/36034 specified by the stimulation parameters

Abstract

A device for transcutaneous electrical stimulation device for affecting gastric function in a patient and a method for performing the same is provided. The device includes a first waveform generator adapted to generate a first waveform having a first frequency capable of stimulating a vagus nerve of the patient at a predetermined location, a second waveform generator adapted to generate a carrier waveform having a second frequency capable of passing from the surface of skin of the patient at the predetermined location, through tissue to the vagus nerve, a modulation device electrically coupled to the first, second and third waveform generators and adapted to modulate the first and carrier waveforms to create a modulated signal, and a first electrode electrically coupled to the modulation device and positioned substantially adjacent to the skin of the mammal, and adapted to apply the modulated signal thereto.

Claims

1. A transcutaneous electrical stimulation device for affecting gastric function in a patient, comprising:

a first waveform generator adapted to generate a first waveform having a first frequency capable of stimulating a vagus nerve of the patient at a predetermined location;

a second waveform generator adapted to generate a carrier waveform having a second frequency capable of passing from the surface of skin of the patient at the predetermined location, through tissue to the vagus nerve;

a modulation device electrically coupled to the first, second and third waveform generators and adapted to modulate the first and carrier waveforms to create a modulated signal; and

a first electrode electrically coupled to the modulation device and positioned substantially adjacent to the skin of the mammal, and adapted to apply the modulated signal thereto.

2. The device according to claim 1, wherein the first and second waveform generators and the electrode are positioned within a patch device having an adhesive thereon for securing the patch to the skin.

3. The device according to claim 2, wherein the predetermined location is a neck region or a lower back region of the patient.

4. The device according to claim 1, further comprising a return electrode for receiving the modulated signal, wherein the first electrode and return electrode are both positioned external of and substantially adjacent to the skin of the mammal, and relative to each other such that the applied modulated signal may pass from the first electrode to the return electrode substantially without passing through tissue of the patient.

5. The device according to claim 1, wherein the first waveform has a frequency of approximately 0.1-40 Hz.

6. The device according to claim 5, wherein the first waveform has a frequency of approximately 0.1-5 Hz.

7. The device according to claim 6, wherein the carrier waveform has a frequency of approximately 100-400 KHz.

8. The device according to claim 6, wherein the carrier waveform has a frequency of approximately 170-210 KHz.

9. The device according to claim 8, wherein the first waveform is a square wave and the carrier waveform is a sinusoidal wave.

10. The device according to claim 1, further comprising a microprocessor adapted to control generation of the first and carrier waveforms by the first and second waveform generators.

11. A method for treating obesity in a patient, comprising:

generating a first waveform having a frequency capable of stimulating a vagus nerve of the patient;

generating a carrier waveform having a frequency capable of passing from the surface of the skin of the patient at a predetermined location, through tissue and to the vagus nerve;

modulating the first and carrier waveforms to create a modulated signal; and

applying the modulated signal package substantially to the skin surface of the patient at the predetermined location to stimulate the vagus nerve to thereby affect gastric function.

12. The method according to claim 11, wherein the step of applying the modulated signal further comprises applying the modulated signal at a frequency sufficiently high to reduce the normal ECA of the patient below approximately 3 beats per minute.

13. The method according to claim 11, wherein the frequency of the first waveform is approximately 0.1-40 Hz.

14. The method according to claim 13, wherein the frequency of the first waveform is approximately 0.1-5 Hz.

15. The method according to claim 14, wherein the frequency of the carrier waveform is approximately 100-400 KHz.

16. The method according to claim 15, wherein the frequency of the carrier waveform is approximately 170-210 KHz.

17. The method according to claim 11, wherein the predetermined location is a neck region of the patient or a lower back region of the patient.