System and method for heightening a humoral immune response

• US 20080133145A1
• Filed: 09/10/2007
• Published: 06/05/2008
• Est. Priority Date: 08/24/2004
• Status: Abandoned Application

• Current Assignee: Searete LLC (Intellectual Ventures LLC)
• Original Assignee: Searete LLC (Intellectual Ventures LLC)
• Inventors: Ishikawa, Muriel Y., Myhrvold, Nathan P., Jung, Edward K.Y., Wood, Lowell L., Wilson, Richa
• Application Number:
  US11/900,442
• Publication Number:
  US 20080133145A1
• Time in Patent Office: Days
• US Class Current: 702/20
• CPC Class Codes: A61K 39/00 Medicinal preparations containing antigens or antibodies materials for immunoassay G01N33/53
• CPC Class Codes: A61P 37/02 Immunomodulators
• CPC Class Codes: G16B 10/00 ICT specially adapted for evolutionary bioinformatics, e.g. phylogenetic tree construction or analysis
• CPC Class Codes: G16B 20/00 ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
• CPC Class Codes: G16B 20/20 Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
• CPC Class Codes: G16B 20/30 Detection of binding sites or motifs
• CPC Class Codes: G16B 20/50 Mutagenesis
• CPC Class Codes: G16B 40/00 ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
• CPC Class Codes: G16B 40/10 Signal processing, e.g. from mass spectrometry [MS] or from PCR
• CPC Class Codes: G16B 5/00 ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
• CPC Class Codes: G16B 5/20 Probabilistic models
• CPC Class Codes: G16H 70/20 relating to practices or guidelines
• CPC Class Codes: G16H 70/60 relating to pathologies
• CPC Class Codes: Y02A 90/10 Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

The present application relates, in general, to a system and/or method for detection and/or treatment.

Claims

1-80. -80. (canceled)

81. A program product, comprising:

at least one signal-bearing medium including one or more instructions for providing one or more computable epitopes of one or more agents associated with at least a part of an immune response in a host; and

one or more instructions for forming a set of the one or more computable epitopes operable for modulating the at least a part of the immune response in the host.

88. The program product of claim 81, wherein the one or more instructions for forming a set of the one or more computable epitopes operable for modulating the at least a part of the immune response in the host comprises:

one or more instructions for forming a set including at least one substantially linear computable epitope.

89. The program product of claim 81, comprising:

one or more instructions for displaying one or more sequences corresponding to the one or more computable epitopes of the one or more agents.

90. The program product of claim 81, comprising:

one or more instructions for projecting one or more alternate courses of the at least a part of the immune response of the host associated with the one or more computable epitopes of the one or more agents.

91. The program product of claim 81, wherein the one or more instructions for providing one or more computable epitopes of one or more agents associated with at least a part of an immune response in a host comprises:

one or more instructions for projecting at least one pattern of change in the one or more computable epitopes of the one or more agents associated with the at least a part of the immune response of the host.

92. The program product of claim 81, wherein the one or more instructions for providing one or more computable epitopes of one or more agents associated with at least a part of an immune response in a host comprises:

one or more instructions for projecting at least one pattern of change in the one or more computable epitopes of the one or more agents in response to a treatment.

93. The program product of claim 81, wherein the one or more instructions for forming a set of the one or more computable epitopes operable for modulating the at least a part of the immune response in the host comprises:

one or more instructions for forming a set of the one or more computable epitopes of the one or more agents amenable to a treatment.

94. The program product of claim 81, wherein the one or more instructions for forming a set of the one or more computable epitopes operable for modulating the at least a part of the immune response in the host comprises:

one or more instructions for forming a set of the one or more computable epitopes including at least one meta-signature.

82. (canceled)

83. (canceled)

84. A program product, comprising:

at least one signal-bearing medium including one or more instructions for providing one or more epitopes of one or more agents associated with at least a part of an immune response in a host; and

one or more instructions for forming a set of the one or more epitopes operable for modulating the at least a part of the immune response in the host.

95. The program product of claim 84, wherein the one or more instructions for forming a set of the one or more epitopes operable for modulating the at least a part of the immune response in the host comprises:

one or more instructions for forming a set including at least one substantially linear epitope.

96. The program product of claim 84, comprising:

one or more instructions for displaying one or more sequences corresponding to the one or more epitopes of the one or more agents.

97. The program product of claim 84, comprising:

one or more instructions for projecting one or more alternate courses of the at least a part of the immune response of the host associated with the one or more epitopes of the one or more agents.

98. The program product of claim 84, wherein the one or more instructions for providing one or more epitopes of one or more agents associated with at least a part of an immune response in a host comprises:

one or more instructions for projecting at least one pattern of change in the one or more epitopes of the one or more agents associated with the at least a part of the immune response of the host.

99. The program product of claim 84, wherein the one or more instructions for providing one or more epitopes of one or more agents associated with at least a part of an immune response in a host comprises:

one or more instructions for projecting at least one pattern of change in the one or more epitopes of the one or more agents in response to a treatment.

100. The program product of claim 84, wherein the one or more instructions for forming a set of the one or more epitopes operable for modulating the at least a part of the immune response in the host comprises:

one or more instructions for forming a set of the one or more epitopes of the one or more agents amenable to a treatment.

101. The program product of claim 84, wherein the one or more instructions for forming a set of the one or more epitopes operable for modulating the at least a part of the immune response in the host comprises:

one or more instructions for forming a set of the one or more epitopes including at least one meta-signature.

85. (canceled)

86. (canceled)

87. A program product, comprising:

at least one signal-bearing medium including one or more instructions for providing one or more computable antigens of one or more agents associated with at least a part of an immune response in a host; and

one or more instructions for forming a set of the one or more computable antigens operable for modulating the at least a part of the immune response in the host.

102. The program product of claim 87, wherein the one or more instructions for forming a set of the one or more computable antigens operable for modulating the at least a part of the immune response in the host comprises:

one or more instructions for forming a set including at least one substantially linear computable antigen.

103. The program product of claim 87, comprising:

one or more instructions for displaying one or more sequences corresponding to the one or more computable antigens of the one or more agents.

104. The program product of claim 87, comprising:

one or more instructions for projecting one or more alternate courses of the at least a part of the immune response of the host associated with the one or more computable antigens of the one or more agents.

105. The program product of claim 87, wherein the one or more instructions for providing one or more computable antigens of one or more agents associated with at least a part of an immune response in a host comprises:

one or more instructions for projecting at least one pattern of change in the one or more computable antigens of the one or more agents associated with the at least a part of the immune response of the host.

106. The program product of claim 87, wherein the one or more instructions for providing one or more computable antigens of one or more agents associated with at least a part of an immune response in a host comprises:

one or more instructions for projecting at least one pattern of change in the one or more computable antigens of the one or more agents in response to a treatment.

107. The program product of claim 87, wherein the one or more instructions for forming a set of the one or more computable antigens operable for modulating the at least a part of the immune response in the host comprises:

one or more instructions for forming a set of the one or more computable antigens of the one or more agents amenable to a treatment.

108. The program product of claim 87, wherein the one or more instructions for forming a set of the one or more computable antigens operable for modulating the at least a part of the immune response in the host comprises:

one or more instructions for forming a set of the one or more computable antigens including at least one meta-signature.