SYSTEM AND METHOD FOR INDIVIDUALIZED PATIENT CARE

• US 20080133267A1
• Filed: 11/29/2007
• Published: 06/05/2008
• Est. Priority Date: 11/30/2006
• Status: Abandoned Application

• Current Assignee: California Institute of Technology
• Original Assignee: California Institute of Technology
• Inventors: Scherer, Axel, Maltezos, George
• Application Number:
  US11/947,758
• Publication Number:
  US 20080133267A1
• Time in Patent Office: Days
• US Class Current: 705/2
• CPC Class Codes: G06Q 10/10 Office automation; Time management
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

A system for individualized patient care, including: a microfluidic bodily fluid reader, programmable to search for different species or components in a bodily fluid inserted in the microfluidic bodily fluid reader; a local computer analysis unit configured to receive data from the microfluidic reader; and a centralized server connectable to the local computer analysis unit. Additionally, a method for monitoring a patient'"'"'s health is shown, including: reviewing medical history and current medical status of a patient; determining which species of a patient'"'"'s bodily fluid should be monitored; preparing a microfluidic bodily fluid reader containing reagents for analysis of the species to be monitored; saving patient history and patient'"'"'s current state; testing the patient with the microfluidic bodily fluid reader; analyzing patient data based on the testing and issuing an alert in case an abnormality is found; further analyzing the patient data for trends indicating that other tests should be added or removed; and adding or removing the other tests through personalization of the microfluidic bodily fluid reader.

Claims

1. A system for individualized patient care, comprising:

a microfluidic bodily fluid reader, programmable to search for different species or components in a bodily fluid inserted in the microfluidic bodily fluid reader;

a local computer analysis unit configured to receive and analyze data from the microfluidic reader; and

a centralized server connectable to the local computer analysis unit.

2. The system of claim 1, wherein the microfluidic reader is adapted to be personalized through selection of the different species or components to be searched for, upon a determination based, at least in part, on results of comparisons made through the centralized server.

3. The system of claim 2, wherein the comparisons are made between the bodily fluid under test and one or more of the following:

individual patient history;

patient'"'"'s blood pressure;

patient'"'"'s stress level;

patient'"'"'s food intake;

medicines taken by the patient;

patient'"'"'s race;

patient'"'"'s sex;

patient'"'"'s age;

patient'"'"'s weight;

patient'"'"'s amount of exercise;

previous blood levels;

family history; and

anonymous aggregate data from other patients.

4. The system of claim 2, wherein the personalized microfluidic reader is provided to the patient to replace the microfluidic reader currently used by the patient.

5. The system of claim 2, wherein the microfluidic reader is personalized by changing the tests in order to perform research across specific groups of patients with certain characteristics or in order to take into account the changing health of the patients.

6. The system of claim 1, wherein the centralized server is connected to the local computer analysis unit through a one-way or two-way data transfer connection.

7. The system of claim 6, wherein the two-way data transfer connection is selected from one or more of the following connections:

an Internet connection, and an encrypted connection.

8. The system of claim 1, wherein the centralized server is connectable to at least one between a doctor, researchers and biotech companies, wherein connection to the doctor is for sending patient specific information to the doctor, and connection to the researchers or biotech companies is for sending anonymous information to the researchers or biotech companies.

9. The system of claim 1, wherein patient data are stored on the centralized server to be made available for the patient or patient'"'"'s relatives.

10. The system of claim 1, wherein lifetime patient data are stored and analyzed on the centralized server.

11. The system of claim 2, wherein personalization of the microfluidic reader occurs automatically.

12. The system of claim 1, wherein the system acts as a pandemic monitor.

13. The system of claim 1, wherein the microfluidic reader is programmed to include chemicals for a species of interest in epidemiological studies and monitoring.

14. The system of claim 1, wherein the bodily fluid is selected from the group consisting of blood, saliva, urine, vaginal fluids, breast milk, pus, tears, earwax, mucous, feces, and semen.

15. A method for monitoring a patient'"'"'s health comprising:

reviewing medical history and current medical status of a patient;

deciding which species of a patient'"'"'s bodily fluid should be monitored;

preparing a microfluidic bodily fluid reader for analysis of the species to be monitored;

saving patient history and patient'"'"'s current state;

testing the patient with the microfluidic bodily fluid reader;

analyzing patient data based on the testing and issuing an alert in case an abnormality is found;

further analyzing the patient data for trends indicating that other tests should be added or removed; and

adding or removing the other tests through personalization of the microfluidic bodily fluid reader.

16. The method of claim 15, wherein patient data is also monitored for long term trends and a further alert is issued in case a long term trend abnormality is found.

17. The method of claim 15, wherein the bodily fluid is selected from the group consisting of blood, saliva, urine, vaginal fluids, breast milk, pus, tears, earwax, mucous, feces and semen.

18. The method of claim 15, wherein the species is a protein.

19. The method of claim 15, wherein the step of further analyzing the patient data for trends indicating that other tests should be added or removed comprises

comparing the patient data to anonymous data to determine how the patient is doing with regards to one or more statistical cohorts;

and

based on comparison between the patient data and the anonymous data changing testing of the patient or warning the patient.

20. The method of claim 15, wherein the step of further analyzing the patient data for trends indicating that other tests should be added or removed comprises adding additional tests in order to perform research across specific groups of individuals with certain characteristics of interest to researchers.

21. The method of claim 15, wherein the step of further analyzing the patient data for trends indicating that other tests should be added or removed comprises identifying sub populations of patients that will and will not benefit from a certain drug.

22. A large scale medical data monitoring method, comprising:

searching for different species or components in a bodily fluid of a patient, through insertion of the bodily fluid in a microfluidic bodily fluid reader;

receiving medical data from the microfluidic reader at a local computer analysis unit;

sending received medical data from the local computer analysis unit to a centralized server; and

comparing medical data of people in a first category with medical data of people in a second category to determine whether the people in the first category have a good response to a certain drug with respect to the people in the second category.

23. The method of claim 22, wherein the first category is a category of overexpressors containing people who overexpress a certain protein.

24. The method of claim 22, wherein the step of comparing medical data is to compare drugs.

25. A method for periodically monitoring a disease marker, comprising:

searching for the disease marker through a microfluidic bodily fluid reader programmable to search for different species or components in a bodily fluid inserted in the microfluidic bodily fluid reader;

analyzing data from the microfluidic bodily fluid reader at a local computer analysis unit, the local computer analysis unit configured to be connected to a centralized server;

alerting a doctor if the disease marker appears; and

further performing the searching periodically.