DERMATOLOGICAL COMPOSITION

• US 20080138451A1
• Filed: 09/19/2007
• Published: 06/12/2008
• Est. Priority Date: 11/26/2003
• Status: Active Grant

• Current Assignee: EI, LLC (Steris PLC)
• Original Assignee: Harmony Labs Incorporated
• Inventors: Wagoner, Bruce Kevin
• Granted Patent: US 7,625,575 B2
• Time in Patent Office: Days
• US Class Current: 424/757
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 36/185 Magnoliopsida (dicotyledons)
• CPC Class Codes: A61K 36/28 Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
• CPC Class Codes: A61K 36/48 Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
• CPC Class Codes: A61K 8/922 of vegetable origin
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61Q 15/00 Anti-perspirants or body deodorants deodorisation of air A61L9/00
• CPC Class Codes: A61Q 3/00 Manicure or pedicure preparations

Abstract

Dermatological compositions containing a humectant, e.g., at least one of urea, ammonium lactate, and glycerin, and an emollient, e.g., at least one of Shea or cocoa butter, glycine soja sterol and hybrid sunflower oil. The compositions of the invention may be utilized for treatment or amelioration of skin disorders or adverse physiological conditions, and such compositions may be employed as a base for cosmetic or pharmaceutical formulations for dermal administration.

Claims

1. A dermatological composition, comprising the following components in the following respective concentration ranges:

2. A dermatological composition according to claim 1, wherein the concentration of urea is in a range of from about 5 to about 40 weight %.

3. A dermatological composition according to claim 1, wherein the concentration of urea is in a range of from about 21 to about 40 weight %.

4. A dermatological composition according to claim 1, further comprising water.

5. A dermatological composition according to claim 1, wherein the composition is an aqueous formulation comprising the following components in the following respective concentrations:

6. The composition of claim 5, in the form of a suspension.

7. A dermatological composition according to claim 1, wherein the composition is an aqueous formulation comprising the following components in the following respective concentrations:

8. The composition of claim 7, in the form of an emulsion.

9. A method of treating skin, tissue or nails, comprising application thereto of a composition as claimed in claim 1.

10. The method of claim 9, comprising cosmetic treatment.

11. The method of claim 9, comprising debriding skin, softening tissue, or softening nails.

12. The method of claim 9, comprising therapeutic treatment.

13. The method of claim 9, comprising treating skin for a condition selected from the group consisting of psoriasis, xerosis, ichthoyosis, keratosis, keratoderma, dermatitis, pruritis, eczema, and calluses.

14. A dermatological composition, comprising the following components:

Urea, Glycerin, Butyrospermum Parkii (Shea Butter) Fruit, Helianthus Annuus (Hybrid Sunflower) Oil and at least one additive selected from the group consisting of antioxidants, chelants, emulsifiers, thickeners, and pH adjustment agents.

15. The dermatological composition of claim 14, wherein the at least one additive comprises wax, polyacrylamide, paraffin, lauric acid, laureth, disodium EDTA, and butylated hydroxytoluene.

16. The dermatological composition of claim 14, further comprising water.

17. The dermatological composition of claim 14, comprising Urea, Glycerin, Butyrospermum Parkii (Shea Butter) Fruit, Helianthus Annuus (Hybrid Sunflower) Oil, wax, polyacrylamide, paraffin, laureth, disodium EDTA, BHT, and water.

18. The dermatological composition of claim 14, comprising the following components in the following respective concentration ranges:

19. The dermatological composition of claim 18, wherein the concentration of urea is 40%.

20. The dermatological composition of claim 14, in a form selected from the group consisting of lotions, creams, ointments, emulsions, suspensions and gels.