Device and method for non-invasive optical detection of chemical and physical blood values and body content substances

• US 20080139906A1
• Filed: 11/19/2007
• Published: 06/12/2008
• Est. Priority Date: 11/20/2006
• Status: Abandoned Application

• Current Assignee: Zimmer MedizinSysteme GmbH
• Original Assignee: Zimmer MedizinSysteme GmbH
• Inventors: Bussek, Karlheinz
• Application Number:
  US11/986,015
• Publication Number:
  US 20080139906A1
• Time in Patent Office: Days
• US Class Current: 600/322
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: G01N 21/314 with comparison of measurements at specific and non-specific wavelengths dual wavelength spectrometry G01J3/427

Abstract

Disclosed are a device and a method for noninvasive determination of body content substances, and to the validation of chemical and physical characteristics of blood and other body fluids. In particular, a noninvasive determination of the blood pressure is disclosed, in connection with other blood values of arterial blood, using optical methods at a patient interface, including the first device in the form of a optical transmitter and a second device in the form of an optical receiver, wherein the optical transmitter and the optical receiver are synchronized with each other by means of a control unit.

Claims

1. A device for noninvasive optical detection of chemical and physical blood values and body content substances at a patient interface comprising:

at least one transmitter device in the form of an optically tunable transmitter and

at least one associated receiver device in the form of an optically tunable receiver,

wherein the at least one optically tunable transmitter and the at least one associated optically tunable receiver are synchronized relative to each other by means of an associated control unit.

2. The device according to claim 1, wherein a blood pressure can be determined by means of data detected at the optically tunable receiver.

3. The device according to claim 1, wherein the control unit and a processing unit are combined into a control and processing unit.

4. The device according to claim 1, wherein the optical transmitter is continuously variably tunable by means of a first device over a frequency range.

5. The device according to claim 1, wherein the optical receiver is continuously variably tunable by means of a second device over a frequency range.

6. The device according to claim 4, wherein the optical transmitter is continuously variably tunable by means of the first device from the UV frequency range over the visible frequency range to the infrared frequency range.

7. The device according to claim 5, wherein the optical receiver is continuously variably tunable by means of the second device from the UV frequency range over the visible frequency range to the infrared frequency range.

8. The device according to claim 1, wherein the optical receiver is continuously variably tunable by means of an optical grid over a frequency range.

9. The device according to claim 1, wherein the optical receiver is continuously variably tunable by means of an optical prism over a frequency range.

10. The device according to claim 1, wherein the optical receiver is continuously variably tunable by means of electronic narrow band filters over a frequency range.

11. The device according to claim 1, wherein the optical transmitter emits a narrow band, almost monochromatic light.

12. The device according to claim 1, wherein the optical transmitter emits coherent light.

13. The device according to claim 1, wherein the optical transmitter emits polarized light in addition to non-polarized light.

14. The device according to claim 1, wherein the transmitter comprises one or several optical transmission units, or separate optically tunable transmitters.

15. The device according to claim 1, wherein the receiver comprises several optical receiver units, or separate optically tunable receivers.

16. The device according to claim 14, wherein the optical transmitters are synchronized respectively to at least one of the two optical receivers by means of the control unit.

17. The device according to claim 16, wherein the control unit determines the chemical and physical values of the body content substances and the blood pressure from the detected differential signals of at least one optically tunable receiver from different signals of the optically tunable transmitters by means of a differential analysis method.

18. The device according to claim 17, wherein the control and processing unit determines additional values with respect to the flow conditions within the body fluids by means of the Doppler effect.

19. The device according to claim 1, wherein the synchronization of the optically tunable transmitter(s) and of the optically tunable receiver(s) and the validation of the determined signals is performed by means of a control unit and a microprocessor.

20. The device according to claim 1, wherein the receiver is a spectrum analyzer with an integrated processing device.

23. The method according to claim 21, wherein the method is performed by means of at least one synchronized and optically tunable transmitter and at least one associated synchronized and optically tunable receiver, using a device comprising the features according to one of the claims 1 through 20.

21. A method for optical detection of chemical and physical blood values and body content substances at a patient interface by means of at least one optically tunable transmitter and at least one associated optically tunable receiver, using a control unit for synchronizing the at least one transmitter and the at least one associated receiver with each other, comprising the following steps:

a) imparting a narrow band electromagnetic radiation into the patient interface by means of the at least one optically tunable transmitter;

b) validating the signals detected after passing the patient interface in the at least one associated optically tunable receiver; and

c) calibrating the determined measurement data by means of a calibration process.

22. The method according to claim 21, wherein the correlated arterial blood pressure is validated and determined by means of the control unit from the signals detected in the receiver unit and from the concentration values of body content substances resulting there from.