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Multi-Wavelength Spatial Domain Near Infrared Oximeter to Detect Cerebral Hypoxia-Ischemia

  • US 20080139908A1
  • Filed: 11/13/2007
  • Published: 06/12/2008
  • Est. Priority Date: 05/13/2005
  • Status: Abandoned Application
First Claim
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1. A method for measuring brain oxygen saturation using multi-wavelength near infrared spectroscopy (NIRS), comprising the steps of:

  • sending light of a first near infrared wavelength through an amount of brain tissue, with the assistance of a near infrared light emitter;

    measuring a first set of at least three intensities of the light of the first near infrared wavelength that passes through the brain tissue, with the assistance of at least three photodiode detectors positioned at least three distances from the near infrared light emitter;

    sending light of a second near infrared wavelength through an amount of brain tissue, with the assistance of the near infrared light emitter;

    measuring a second set of at least three intensities of the light of the second near infrared wavelength that passes through the brain tissue, with the assistance of the at least three photodiode detectors positioned at the at least three distances from the near infrared light emitter;

    sending light of a third near infrared wavelength through an amount of brain tissue, with the assistance of the near infrared light emitter;

    measuring a third set of at least three intensities of the light of the third near infrared wavelength that passes through the brain tissue, with the assistance of at least three photodiode detectors positioned at the at least three distances from the near infrared light emitter; and

    calculating a saturation of tissue oxygenation using an algorithm derived from the Beer-Lambert law and based at least upon one or more ratios of measured intensities at two or more near infrared wavelengths and one or more ratios of measured intensities at two or more photodiode detectors.

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