Method for manufacturing an electrokinetic infusion pump

• US 20080149599A1
• Filed: 12/21/2006
• Published: 06/26/2008
• Est. Priority Date: 12/21/2006
• Status: Abandoned Application

• Current Assignee: Lifescan Incorporated (Duv Holding Corporation)
• Original Assignee: Lifescan Incorporated (Duv Holding Corporation)
• Inventors: Wiard, Richard, Bohm, Sebastian
• Application Number:
  US11/614,521
• Publication Number:
  US 20080149599A1
• Time in Patent Office: Days
• US Class Current: 216/94
• CPC Class Codes: F04B 43/0054 particularities of the flexible members
• CPC Class Codes: Y10T 156/10 Methods of surface bonding and/or assembly therefor
• CPC Class Codes: Y10T 156/1039 Surface deformation only of sandwich or lamina [e.g., embossed panels]
• CPC Class Codes: Y10T 156/1052 with cutting, punching, tearing or severing
• CPC Class Codes: Y10T 29/49236 Fluid pump or compressor making

Abstract

A method for producing a porous flow-through element for use in an electrokinetic infusion pump is provided and generally includes providing a porous membrane that is entirely porous along both its length and width, treating the membrane by selectively inactivating portions of the membrane in a desired pattern to define active regions that allow fluid flow therethrough and inactive regions that do not, and laminating the treated membrane. Various techniques can be used to treat the membrane including, for example, applying a heated embossing die to the membrane, contacting selected portions of the membrane with laser energy, applying a pore-penetrating chemical to the membrane, and cutting and removing selected portions of the membrane. The resulting treated membrane can be laminated between opposed films having one or more perforations therethrough with each perforation being aligned with an active region to define a fluid flow pathway therebetween.

Claims

1. A method for producing a porous flow-through element of an electrokinetic infusion pump, comprising:

providing a porous membrane that is entirely porous along both its length and width;

treating the membrane by selectively inactivating portions of the membrane in a desired pattern to define active regions that allow fluid flow therethrough and inactive regions that do not; and

laminating the treated membrane.

2. The method of claim 1, wherein the treated membrane is laminated between first and second sheets of lamination film, the first and second sheets each having one or more perforations therethrough, each of the perforations being aligned with an active region of the treated membrane such that the resulting laminated membrane has a perforation at a top portion and a bottom portion of each active region to define a fluid flow pathway therebetween.

3. The method of claim 1, further comprising cutting the laminated membrane to yield a plurality of porous flow-through elements each having a top lamination film that is fluid impervious with at least one perforation that is positioned adjacent an active region of the membrane and a bottom lamination film that is fluid impervious with at least one perforation that is positioned adjacent an active region of the membrane.

4. The method of claim 3, wherein the perforations of the top and bottom lamination films are positioned at opposite ends of the porous flow-through element such that fluid is able to flow from one perforation longitudinally through the active region of the membrane and through the perforation in the opposite film.

5. The method of claim 3, wherein the perforations of the top and bottom lamination films are aligned such that fluid flows from one perforation through the active region of the membrane in a direction transverse to a longitudinal axis of the porous membrane and through the perforation in the opposite film.

6. The method of claim 3, further comprising assembling an electrokinetic infusion pump by inserting the porous flow-through element into a chamber of the pump.

7. The method of claim 1, wherein treating the membrane comprises applying a heated embossing die to the membrane to selectively inactivate portions of the membrane in a desired pattern.

8. The method of claim 1, wherein treating the membrane comprises contacting selected portions of the porous membrane with laser energy to selectively inactivate portions of the membrane in a desired pattern.

9. The method of claim 1, wherein treating the membrane comprises applying a pore-penetrating chemical to the membrane to selectively inactivate portions of the membrane in a desired pattern.

10. The method of claim 9, wherein the pore-penetrating chemical is an ink.

11. The method of claim 1, wherein treating the membrane comprises cutting and removing selected portions of the membrane to create a desired pattern.

12. The method of claim 11, wherein cutting the membrane comprises applying a rotating die cutter to the membrane.

13. The method of claim 1, wherein treating the membrane and laminating the treated membrane is performed as a continuous process.

14. The method of claim 1, wherein an adhesive material selected from the group consisting of pressure sensitive adhesive, heat sensitive adhesive, and UV curable adhesive is applied between the porous membrane and the first and second sheets of lamination film prior to laminating.

15. The method of claim 1, wherein the porous membrane is in sheet form.

16. The method of claim 3, wherein the porous flow-through element has a thickness in the range of about 10 micrometers to 2 millimeters.

17. The method of claim 1, wherein the porous membrane is made from a material selected from the group consisting of polyvinylidene fluoride (PVDF), nylons, polytetrafluoroethylene (PTFE), cellulose, nitro-cellulose, porous alumina, papers, porous ceramics, and polyethylene.

18. A method for producing a porous flow-through element of an electrokinetic infusion pump, comprising:

providing a porous membrane that is entirely porous along both its length and width;

treating the membrane by selectively inactivating portions of the membrane in a desired pattern to define active regions that allow fluid flow therethrough and inactive regions that do not;

laminating the treated membrane;

cutting the laminated membrane to yield a plurality of porous flow-through elements; and

inserting the porous flow-through element into a chamber of an electrokinetic infusion pump.

19. The method of claim 18, wherein the treated membrane is laminated between first and second sheets of lamination film, the first and second sheets each having one or more perforations therethrough, each of the perforations being aligned with an active region of the treated membrane such that the resulting laminated membrane has a perforation at a top portion and a bottom portion of each active region to define a fluid flow pathway therebetween.

20. The method of claim 19, wherein each porous flow-through element has a top lamination film that is fluid impervious with at least one perforation that is positioned adjacent an active region of the membrane and a bottom lamination film that is fluid impervious with at least one perforation that is positioned adjacent an active region of the membrane.