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Fluorescence Detector for Microfluidic Diagnostic System

  • US 20080149840A1
  • Filed: 11/14/2007
  • Published: 06/26/2008
  • Est. Priority Date: 03/24/2006
  • Status: Active Grant
First Claim
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1. A diagnostic apparatus, comprising:

  • one or more microfluidic channels configured to amplify one or more polynucleotides; and

    one or more fluorescence detectors configured to detect presence of the one or more polynucleotides in the one or more channels by detecting fluorescent light emitted from a probe associated with the one or more polynucleotides, wherein the one or more detectors each comprise;

    a first LED emitting light of a first color;

    a second LED emitting light of a second color;

    a first photodiode configured to collect emitted light of the first color;

    a second photodiode configured to collect emitted light of the second color;

    and wherein the first and second photodiodes are each connected to a pre-amplifier circuit having a time-constant of less than of about 1 second.

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