Method of therapeutic drug monitoring
First Claim
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1. A method of using a diffusion-based, continuous-monitoring system to monitor the effectiveness of delivering a therapeutic drug, the method comprising the acts of:
- creating at least one diffusion channel in an area of skin;
maintaining the at least one diffusion channel for a desired duration;
continuously monitoring the levels of the therapeutic drug, the levels of a metabolite of the therapeutic drug or the levels of a substance that is affected by the therapeutic drug in the area of the skin for the desired duration via a diffusion-based, continuous-monitoring device; and
analyzing the levels of the therapeutic drug, the metabolite of the therapeutic drug or the substance that is affected by the therapeutic drug so as to determine the effectiveness of delivering the therapeutic drug.
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Abstract
A method of using a diffusion-based, continuous-monitoring system to monitor the effectiveness of delivering a drug includes creating and maintaining a diffusion channel in an area of skin. The levels of the drug, metabolite, or affected substance of the drug are continuously monitored in the area of the skin for a desired duration via a diffusion-based, continuous-monitoring device. The levels of the drug, the metabolite, or affected substance is analyzed to determine the effectiveness of delivering the therapeutic drug.
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Citations
23 Claims
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1. A method of using a diffusion-based, continuous-monitoring system to monitor the effectiveness of delivering a therapeutic drug, the method comprising the acts of:
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creating at least one diffusion channel in an area of skin; maintaining the at least one diffusion channel for a desired duration; continuously monitoring the levels of the therapeutic drug, the levels of a metabolite of the therapeutic drug or the levels of a substance that is affected by the therapeutic drug in the area of the skin for the desired duration via a diffusion-based, continuous-monitoring device; and analyzing the levels of the therapeutic drug, the metabolite of the therapeutic drug or the substance that is affected by the therapeutic drug so as to determine the effectiveness of delivering the therapeutic drug. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method of using a diffusion-based, continuous-monitoring system to monitor the effectiveness of delivering a therapeutic drug, the method comprising the acts of:
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creating at least one diffusion channel in an area of skin; topographically applying a hydrogel or liquid on the skin to assist in enhancing the diffusion of the therapeutic drug, a metabolite of the therapeutic drug or a substance that is effected by the therapeutic drug; maintaining the at least one diffusion channel for a desired duration; positioning a diffusion-based, continuous monitoring device in communication with the hydrogel or liquid; continuously monitoring the levels of the therapeutic drug, the levels of a metabolite of the therapeutic drug or the levels of a substance that is affected by the therapeutic drug in the area of the skin via the diffusion-based, continuous monitoring device; and analyzing the levels of the therapeutic drug, the metabolite of the therapeutic drug or the substance that is affected by the therapeutic drug so as to determine the effectiveness of delivering the therapeutic drug. - View Dependent Claims (15, 16, 17)
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18. A method of using a diffusion-based, continuous-monitoring system to monitor the effectiveness of delivering a therapeutic drug, the method comprising the acts of:
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providing a diffusion-based, continuous-monitoring device, the device including a communications interface that is adapted to connect with a receiving module via a communications link; creating at least one diffusion channel in an area of skin; maintaining the at least one diffusion channel for a desired duration; continuously monitoring the levels of the therapeutic drug, the levels of a metabolite of the therapeutic drug or the levels of a substance that is affected by the therapeutic drug in the area of the skin for the desired duration via the diffusion-based, continuous-monitoring device; and analyzing the levels of the therapeutic drug, the metabolite of the therapeutic drug or the substance that is affected by the therapeutic drug so as to determine the effectiveness of delivering the therapeutic drug. - View Dependent Claims (19, 20, 21, 22, 23)
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Specification