High Performance Imaging System for Diffuse Optical Tomography and Associated Method of Use
First Claim
1. An imaging system for diffuse optical tomography comprising:
- a plurality of light sources that are each connected to a digital input power source;
a plurality of light conduits are connected to the plurality of light sources;
an optode grid that is attachable to a portion of a human subject, wherein the optode grid design is connected to the plurality of light conduits;
a plurality of discrete, isolated, light detectors that are operatively connected to the optode grid for instantaneously detecting light provided by the plurality of light sources after interacting with the human subject; and
a plurality of analog to digital converters for converting a plurality of individual signals from the plurality of discrete, isolated, light detectors into a plurality of digital signals.
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Accused Products
Abstract
A high performance imaging system for diffuse optical tomography is disclosed. A dense grid utilizing sources, e.g., light emitting diodes (“LEDs”), that achieve high performance at high speed with a high dynamic range and low inter-channel crosstalk are complemented by a system of discrete, isolated receivers, e.g., avalanche photodiodes (“APDs”). The source channels have dedicated reconfigurable encoding control signals, and the detector channels have reconfigurable decoding, allowing maximum flexibility and optimal mixtures of frequency and time encoding and decoding. Each detector channel is analyzed by dedicated, isolated, high-bandwidth receiver circuitry so that no channel gain switching is necessary. The resulting improvements to DOT system performance, e.g., increased dynamic range and decreased crosstalk, enable higher density imaging arrays and provide significantly enhanced DOT image quality. A processor can be utilized to provide sophisticated three dimensional modeling as well as noise reduction.
79 Citations
25 Claims
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1. An imaging system for diffuse optical tomography comprising:
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a plurality of light sources that are each connected to a digital input power source; a plurality of light conduits are connected to the plurality of light sources; an optode grid that is attachable to a portion of a human subject, wherein the optode grid design is connected to the plurality of light conduits; a plurality of discrete, isolated, light detectors that are operatively connected to the optode grid for instantaneously detecting light provided by the plurality of light sources after interacting with the human subject; and a plurality of analog to digital converters for converting a plurality of individual signals from the plurality of discrete, isolated, light detectors into a plurality of digital signals. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. An imaging system for diffuse optical tomography comprising:
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a plurality of light emitting diodes that are each connected to a digital input power source that operates at high speed in a high dynamic range; a plurality of fiber optic cables connected in a one-to-one relationship to the plurality of light emitting diodes; an optode grid that is attachable to a portion of a human subject, wherein the optode grid design is connected to the plurality of light conduits; a plurality of avalanche photo diodes that are operatively connected to the optode grid for detecting light provided by the plurality of light emitting diodes after interacting with the human subject; and a plurality of analog to digital converters for converting a plurality of individual signals from the plurality of avalanche photo diodes into a plurality of digital signals.
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20. A method for utilizing an imaging system for diffuse optical tomography comprising:
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attaching an optode grid to a portion of a human subject, wherein the optode grid design is connected to the plurality of light conduits that are connected in a to a plurality of light sources that are electrically connected to a digital input power source; utilizing a plurality of discrete, isolated, light detectors that are operatively connected to the optode grid for instantaneously detecting light provided by the plurality of light sources after interacting with the human subject; and converting a plurality of individual signals from the plurality of discrete, isolated, light detectors into a plurality of digital signals with at least one analog to digital converter. - View Dependent Claims (21, 22, 23, 24, 25)
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Specification