Fluid Sensor and Kit

• US 20080159913A1
• Filed: 01/31/2006
• Published: 07/03/2008
• Est. Priority Date: 02/01/2005
• Status: Abandoned Application

• Current Assignee: Bayer Healthcare LLC (Bayer AG)
• Original Assignee: Bayer Healthcare LLC (Bayer AG)
• Inventors: George, Suny J., Dosmann, Andrew J., Charlton, Steven C., Marfurt, Karen L., Jung, Sung-Kwon
• Application Number:
  US11/795,843
• Publication Number:
  US 20080159913A1
• Time in Patent Office: Days
• US Class Current: 422/57
• CPC Class Codes: A61B 2562/242 Packaging, i.e. for packaging the sensor or apparatus before use
• CPC Class Codes: A61B 5/1411 by percutaneous method, e.g. by lancet
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150213 Venting means
• CPC Class Codes: A61B 5/150274 Manufacture or production processes or steps for blood sampling devices
• CPC Class Codes: A61B 5/150343 Collection vessels for collecting blood samples from the skin surface, e.g. test tubes, cuvettes sampling from within body cavities A61B5/150015, A61B5/150045
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: G01N 21/78 producing a change of colour
• CPC Class Codes: G01N 33/521 Single-layer analytical elements
• CPC Class Codes: G01N 33/528 Atypical element structures, e.g. gloves, rods, tampons, toilet paper
• CPC Class Codes: G01N 33/66 involving blood sugars, e.g. galactose

Abstract

A fluid sensor comprises a formed plastic body and a reagent. The body has a top face with an integral first surface. The body also has a bottom face opposed to the first surface and a sidewall that extends from the periphery of the top face. The first surface is adapted to accept a fluid sample. The reagent is disposed on the integral first surface and causes a color change detectable on the bottom face when the reagent reacts with an analyte in the fluid sample.

Claims

1. A fluid sensor comprising:

a formed plastic body having a top face with an integral first surface, a bottom face opposed to said first surface, and a sidewall extending from the periphery of said top face, said first surface being adapted to accept a fluid sample; and

a reagent being disposed on said integral first surface and adapted to cause a color change detectable on said bottom face when said reagent reacts with an analyte in said fluid sample.

2. The sensor of claim 1, wherein said formed plastic body is a hollow frustum.

3. The sensor of claim 1, wherein said formed plastic body is a hollow frustum with a larger open end and a smaller closed end.

4. The sensor of claim 1, wherein said sidewall has at least one latch.

5. The sensor of claim 4, wherein said at least one latch is an indentation, hole, groove, or emboss.

7. The sensor of claim 1, wherein said color change is measured by a change in reflectance on said bottom face.

8. The sensor of claim 7, wherein said reagent is a glucose dehydrogenase and pyrroloquinoline quinone-based system.

10. The sensor of claim 7, wherein said reagent is a glucose dehydrogenase and diaphorase-based system.

12. The sensor of claim 7, wherein said reagent is a titanium dioxide and polymer matrix.

15. The sensor of claim 1, wherein said top face has a raised region substantially surrounding said integral first surface.

16. The sensor of claim 15, further comprising a lid attached to said raised region.

19. The sensor of claim 16, wherein said lid is a hollow plastic frustum, having a large open end and a smaller closed end, said smaller closed end having a first surface with a plurality of vent holes.

6. (canceled)

9. (canceled)

11. (canceled)

13-14. -14. (canceled)

17-18. -18. (canceled)

20-25. -25. (canceled)

26. A fluid sensor comprising:

a formed porous plastic body having a top face with an integral first surface, a bottom face with a second surface opposed to said first surface, and a sidewall adjacent to said top face, wherein said first surface is adapted to accept a fluid sample;

a surfactant disposed on said body; and

a reagent adapted to cause a color change detectable on said second surface when said reagent reacts with an analyte in said fluid sample.

27. The sensor of claim 26, wherein said reagent is disposed on said second surface and said surfactant is applied to said first surface.

28. The sensor of claim 26, wherein said reagent is disposed on said first surface and said surfactant is applied to said second surface.

33. The sensor of claim 26, wherein said color change is measured by a change in reflectance on said bottom face.

34. The sensor of claim 33, wherein said reagent is a glucose dehydrogenase and pyrroloquinoline quinone-based system.

36. The sensor of claim 33, wherein said reagent is a glucose dehydrogenase and diaphorase-based system.

29-32. -32. (canceled)

35. (canceled)

37-39. -39. (canceled)

40. A blood glucose sensor kit comprising:

a) a sensor package having;

i) a base portion having at least one sensor cavity and at least one desiccant cavity in fluid communication with said sensor cavity,

ii) a desiccant material disposed within said desiccant cavity,

iii) a protective sheet covering said sensor cavity and said desiccant cavity, and

iv) a sensor located in said sensor cavity;

b) a blood glucose meter having;

i) a housing,

ii) a display disposed on said housing, and

iii) a read-head disposed on said housing, said read-head being adapted to detachably engage said sensor; and

c) a guide adapted to cover said protective sheet, said guide having at least one opening adapted to align said read-head to engage said sensor within said sensor cavity.

41-47. -47. (canceled)

48. A blood glucose sensor kit comprising:

a) a sensor package having;

i) a container having an inner surface;

ii) a desiccant liner disposed in said container;

iii) a friction liner disposed in said container; and

iv) at least one sensor located in said container, frictionally engaging said friction liner; and

b) a blood glucose meter having;

i) a housing,

ii) a display disposed on said housing, and

iii) a read-head disposed on said housing, said read-head being adapted to detachably engage said sensor while said sensor is located in said sensor package.

49-58. -58. (canceled)