VASCULAR ACCESS DEVICE ANTIMICROBIAL MATERIALS AND SOLUTIONS

• US 20080161763A1
• Filed: 07/26/2007
• Published: 07/03/2008
• Est. Priority Date: 07/28/2006
• Status: Active Grant

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Isaacson, S. Ray, McKinnon, Austin Jason, Stout, Marty L., Harding, Weston F., Davis, Bryan G., Cindrich, Christopher N., Howell, Glade H., Rasmussen, Wayne K., Christensen, Kelly D.
• Granted Patent: US 8,512,294 B2
• Time in Patent Office: Days
• US Class Current: 604/265
• CPC Class Codes: A61B 1/00188 with focusing or zooming features
• CPC Class Codes: A61M 2039/0036 characterised by a septum having particular features, e.g. having venting channels or being made from antimicrobial or self-lubricating elastomer
• CPC Class Codes: A61M 2039/1072 with a septum present in the connector
• CPC Class Codes: A61M 2205/0222 Materials for reducing friction
• CPC Class Codes: A61M 39/045 pre-slit to be pierced by blunt instrument
• CPC Class Codes: A61M 39/162 with antiseptic agent incorporated within the connector
• CPC Class Codes: A61M 39/26 Valves closing automatically on disconnecting the line and opening on reconnection thereof check valves A61M39/24

Abstract

A medical device includes an antimicrobial layer. A method of depositing an antimicrobial agent on or in the body of a medical device includes inserting a high temperature resistant tube having multiple holes through its surface into a vascular access device and coating, or delivering an antimicrobial agent to, and interior surface of the device.

Claims

1. A medical device comprising:

a body and a septum housed within the body, wherein the septum includes a slit and further having a surface;

a layer, including an antimicrobial agent, disposed on the surface.

2. The medical device of claim 1, wherein the layer includes a solution containing a mixture of the antimicrobial agent and a lube oil, and wherein the solution coats the surface of the slit.

3. The medical device of claim 1, further comprising a second layer in contact with the layer of the device, wherein the second layer includes a lube oil with a low coefficient of friction.

4. The medical device of claim 1, wherein the surface resides in the slit, wherein the layer includes a polymeric coating with a low coefficient of friction, and wherein the coating coals the surface of the slit.

5. The medical device of claim 1, further comprising a second layer in contact with the layer of the device, wherein the second layer includes a polymeric coating with a low coefficient of friction.

6. The medical device of claim 1, wherein the surface is a top surface of the septum, wherein the layer includes a polymeric coating with a low coefficient of friction, and wherein the coating coats the surface.

7. The medical device of claim 6, further comprising a second layer in contact with the layer of the device, wherein the second layer includes a polymeric coating with a low coefficient of friction.

8. The medical device of claim 1, wherein the layer includes a fluorinated silicone.

9. The medical device of claim 1, further comprising:

a second layer in contact with the layer of the device,

wherein the second layer is soluble to a first flush compound,

wherein the second layer is resistant to a second flush compound,

wherein the layer of the device is soluble to a second flush compound, and

wherein the layer of the device is resistant to the first flush compound.

10. The medical device of claim 1, wherein the layer includes a radioactive isotope.

20. The medical device of claim 1, wherein the layer forms a septum housed within the vascular access device, and wherein the layer includes a radioactive isotope.

11. A method of repressing pathogens in a vascular access device, comprising:

providing a vascular access device comprising a body and a septum, the septum having a surface and a slit for providing access through the vascular access device;

providing a layer having an antimicrobial agent; and

disposing the layer on the surface.

12. The method of claim 11, wherein the layer includes a solution containing a mixture of the antimicrobial agent and a lube oil, and wherein the solution coats the surface of the slit.

13. The method of claim 11, further comprising a second layer in contact with the layer of the device, wherein the second layer includes a lube oil with a low coefficient of friction.

14. The method of claim 11, wherein the surface resides in the slit, wherein the layer includes a polymeric coating with a low coefficient of friction, and wherein the coating coats the surface of the slit.

16. The method of claim 11, wherein the surface is a top surface of the septum, wherein the layer includes a polymeric coating with a low coefficient of friction, and wherein the coating coats the surface.

17. The method of claim 16, further comprising a second layer in contact with the layer of the device, wherein the second layer includes a polymeric coating with a low coefficient of friction.

19. The method of claim 11, further comprising:

a second layer in contact with the layer of the device,

wherein the second layer is soluble to a first flush compound,

wherein the second layer is resistant to a second flush compound,

wherein the layer of the device is soluble to a second flush compound, and

wherein the layer of the device is resistant to the first flush compound.

15. The method of claim I1, further comprising a second layer in contact with the layer of the device, wherein the second layer includes a polymeric coating with a low coefficient of friction.

18. The method of claim I 1, wherein the layer includes a fluorinated silicone.

21. A medical device, comprising:

means for accessing the vascular system of a patient, and means for repressing a pathogen,

wherein the pathogen resides within the means for accessing the vascular system of a patient, and

wherein the means for repressing the pathogen includes a slit septum including an antimicrobial agent.

22. The medical device of claim 21 wherein the antimicrobial agent is coated on the surface of the septum.

23. The medical device of claim 21, wherein the antimicrobial agent is mixed with the material of the septum.