Device and method to for independently stimulating hemidiaphragms

• US 20080161878A1
• Filed: 12/26/2007
• Published: 07/03/2008
• Est. Priority Date: 10/15/2003
• Status: Abandoned Application

• Current Assignee: RMX, LLC (ASHINC Corp.)
• Original Assignee: RMX, LLC (ASHINC Corp.)
• Inventors: Province, Rose, Lee, Chang, Ligon, David, Tehrani, Amir J., Hoffmann, Drew, Goodman, Amy
• Application Number:
  US12/005,198
• Publication Number:
  US 20080161878A1
• Time in Patent Office: Days
• US Class Current: 607/42
• CPC Class Codes: A61B 5/08 Detecting, measuring or recording devices for evaluating the respiratory organs A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/389 Electromyography [EMG]
• CPC Class Codes: A61B 5/395 Details of stimulation, e.g. nerve stimulation to elicit EMG response
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00
• CPC Class Codes: A61N 1/3601 of respiratory organs

Abstract

A device and method for treating a subject is provided where electrical stimulation may be separately provided to each hemidiaphragm to cause diaphragm contraction. Fatigue may be avoided among other possible benefits. Each hemidiaphragm may also be stimulated with different stimulation parameters. Stimulation may be smoothly transitioned between hemidiaphragms. Such stimulation may provide an increase in functional residual capacity or other therapeutic effects.

Claims

1. An electrical stimulation device for increasing functional residual capacity of a subject comprising:

an electrical stimulator comprising;

a first stimulation lead configured to electrically stimulate a first hemidiaphragm of a diaphragm; and

a second stimulation lead configured to electrically stimulate a second hemidiaphragm of a diaphragm,

wherein each of said first stimulation lead and said second stimulation lead are independently controllable by the electrical stimulator, wherein the electrical stimulator is configured to provide stimulation to elicit a contraction of at least a portion of at least one of the first hemidiaphragm and the second hemidiaphragm to increase functional residual capacity.

2. The electrical stimulation device of claim 1 wherein the electrical stimulator is configured to provide a first stimulation signal having a first parameter to the first hemidiaphragm, and a second stimulation signal having a second parameter to the second hemidiaphragm.

3. The electrical stimulation device of claim 1 wherein the electrical stimulator is configured to provide a first stimulation signal to the first hemidiaphragm for a first period of time and a second stimulation signal to the second hemidiaphragm for a second period of time wherein the first period of time and the second period of time overlap for third period of time.

4. The electrical stimulation device of claim 3 wherein at least one of said first signal and said second signal comprise a ramped signal during the third period of time.

5. The electrical stimulation device of claim 4 wherein the ramped signal comprises one or more ramped parameter selected from amplitude, frequency, pulse width, burst duration and burst frequency.

6. The electrical stimulation device of claim 3 wherein the electrical stimulator is configure to transition stimulation from the first hemidiaphragm to the second hemidiaphragm so that therapeutic lung volume is maintained throughout transition

7. An electrical stimulation device for increasing functional residual capacity of a subject comprising:

an electrical stimulator comprising;

a first stimulation lead configured to electrically stimulate a first hemidiaphragm of a diaphragm; and

a second stimulation lead configured to electrically stimulate a second hemidiaphragm of a diaphragm,

wherein each of said first stimulation lead and said second stimulation lead are independently controllable by the electrical stimulator, wherein the electrical stimulator is configured to provide stimulation to elicit a contraction of at least a portion of at least one of the first hemidiaphragm and at least a portion of the second hemidiaphragm in a manner that reduces diaphragm fatigue.

8. The electrical stimulation device of claim 7 wherein the stimulation is configured to increase functional residual capacity of a subject.

9. A method for increasing upper airway patency of a subject comprising:

providing a stimulation to a subject to increase a lung volume of the subject; and

reducing the stimulation to the subject to create an exhalation to thereby increase upper airway patency.

10. The method of claim 9 wherein the step of reducing the stimulation comprise reducing the stimulation at an end portion of an inspiration cycle of a respiration cycle.

11. The method of claim 9 wherein the step of reducing the stimulation comprise reducing the stimulation at a beginning portion of an exhalation cycle of a respiration cycle.