AUTOMATED DRUG PREPARATION APPARATUS INCLUDING SERIAL DILUTION FUNCTIONALITY
First Claim
1. An automated drug preparation system for preparing a prescribed dosage of medication in a syringe comprising:
- a first drug delivery station that includes a first automated drug delivery device that is in fluid communication with a source of a first fluid that is for delivery to the syringe;
an adjustable plunger extension mechanism that includes a movable component that intimately engages a plunger of the syringe so that a first movement of the movable component is translated into a first extension of the plunger a first defined distance which causes a first volume of the first fluid to be drawn into the syringe; and
a controller that includes stored medication orders including a final volume and concentration of the prescribed dosage of medication, wherein and based on the stored medication orders, the controller calculates the first defined distance that the plunger is moved to draw the first volume of the first fluid and causes the plunger to extend the first defined distance, wherein when the first volume is less than the final volume, the controller calculates the difference between the final volume and the first volume and disengages the fluid communication between the source of the first fluid and the first automated drug delivery device and then calculates a second defined distance the plunger is to be moved to permit reception of a second volume of a second fluid and causes the plunger to extend the second defined distance, wherein the sum of the first and second volumes is equal to the final volume.
8 Assignments
0 Petitions
Accused Products
Abstract
An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time.
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Citations
29 Claims
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1. An automated drug preparation system for preparing a prescribed dosage of medication in a syringe comprising:
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a first drug delivery station that includes a first automated drug delivery device that is in fluid communication with a source of a first fluid that is for delivery to the syringe; an adjustable plunger extension mechanism that includes a movable component that intimately engages a plunger of the syringe so that a first movement of the movable component is translated into a first extension of the plunger a first defined distance which causes a first volume of the first fluid to be drawn into the syringe; and a controller that includes stored medication orders including a final volume and concentration of the prescribed dosage of medication, wherein and based on the stored medication orders, the controller calculates the first defined distance that the plunger is moved to draw the first volume of the first fluid and causes the plunger to extend the first defined distance, wherein when the first volume is less than the final volume, the controller calculates the difference between the final volume and the first volume and disengages the fluid communication between the source of the first fluid and the first automated drug delivery device and then calculates a second defined distance the plunger is to be moved to permit reception of a second volume of a second fluid and causes the plunger to extend the second defined distance, wherein the sum of the first and second volumes is equal to the final volume. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. An automated drug preparation system for preparing a prescribed dosage of medication in a syringe comprising:
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a first drug delivery station that includes a first automated drug delivery device that is in fluid communication with a source of a first fluid that can be selectively delivered to the syringe; an adjustable plunger extension mechanism that includes a movable component that intimately engages a plunger of the syringe so that a first movement of the movable component is translated into a first extension of the plunger a first defined distance; a controller that includes stored medication orders including a final volume and concentration of the prescribed dosage of medication, wherein and based on the stored medication orders, the controller calculates the first defined distance that the plunger is moved to create a first volume for receiving the dosage of medication and causes the plunger to extend the first defined distance; and a second drug delivery station that delivers medication into the syringe after the plunger has been extended, wherein the first and second drug delivery stations are different from one another in at least one aspect. - View Dependent Claims (10, 11)
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12. An automated drug preparation system for preparing in a syringe a final dosage of medication having a concentration X from a medication source that has a concentration Y which is higher than X comprising:
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a first fluid delivery station that includes a first automated fluid delivery device that is in fluid communication with a source of a first fluid that is for delivery to the syringe; an adjustable plunger extension mechanism that includes a movable component that intimately engages a plunger of the syringe so that a first movement of the movable component is translated into a first extension of the plunger a first defined distance which causes a volume A of the first fluid to be drawn into the syringe; a second fluid delivery station that includes a second automated fluid delivery device that is in fluid communication with the medication source having the concentration Y; a controller that includes stored medication orders including a final volume and the concentration Y of the final dosage of medication, wherein and based on the stored medication orders, the controller calculates the first defined distance that the plunger is moved to draw the volume A of the first fluid and causes the plunger to extend the first defined distance, wherein the second automated fluid delivery device delivers into the syringe an amount B of the medication source that has the concentration Y, wherein the sum of A+B=Y, wherein delivery of the amounts A and B occur at different times. - View Dependent Claims (13, 14, 15, 16, 17)
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18. An automated drug preparation system for preparing a diluted dosage of medication in a drug delivery device comprising:
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an input for entering a drug order; a plurality of stations including a first station at which drug delivery devices are loaded onto a transportation device that moves the drug delivery devices from one station to another station in a controlled manner; a storage unit containing a plurality of drug vials including empty drug vials and drug vials containing medication to produce a dosage of medication having a first concentration that is greater than a second concentration of the diluted dosage of medication; an automated drug preparation device at a second station that executes the drug order and is configured to both deliver fluid and aspirate fluid based on instructions that are contained in a database and associated with the drug order; a third station that holds one or more partially used vials containing reusable medications; and a controller that initially assigns a drug vial to each drug delivery device loaded onto the transportation device based on the final concentration of the diluted dosage of medication and the volume of the diluted dosage of medication, the controller searching an inventory of the drug vials and selecting the drug vial that contains the medication for use in preparing the prescribed dosage and provides a minimum amount of the drug for use in preparing the prescribed dosage and then instructing the automated drug preparation device to prepare and deliver the diluted prescribed dosage of medication. - View Dependent Claims (19, 20, 21, 22, 23, 24)
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25. A method for processing a drug order and preparing a diluted child drug product from a parent drug product, when it is required, comprising the steps of:
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receiving and processing the drug order and determining whether a diluted child drug product is required as is the case when the drug order can not be prepared by processing the parent drug product; determining whether a diluted parent drug product exists and if none exists, then determining whether an amount of reconstituted parent drug product can be aspirated into a syringe and an amount of diluent directly added to the syringe to yield the diluted child drug product; and
if so, then performing these operations; andif the diluted parent drug product exists, then determining whether an amount of the diluted parent drug product can be aspirated into a syringe and an amount of diluent directly added to the syringe to yield the diluted child drug product; and
if so, then performing these operations; and
if the diluted parent drug product does not exist, then the parent drug product is located and an amount of the parent drug product is aspirated into an empty container and an amount of diluent is added to the container which is then manipulated to produce the child drug product.
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26. An automated drug preparation system for preparing a prescribed diluted dosage of medication in a syringe comprising:
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a first drug delivery station that includes a first automated drug delivery device that is in fluid communication with a source of a diluent that is for delivery to the syringe; an adjustable plunger extension mechanism that includes a movable component that intimately engages a plunger of the syringe so that a first movement of the movable component is translated into a first extension of the plunger a first defined distance which causes a first volume of the diluent to be drawn into the syringe; a second drug delivery station that includes a second automated drug delivery device which reconstitutes medication in a drug vial by adding a volume of diluent to the medication in the drug vial to produce a dosage of medication having a first concentration; and a controller that includes stored medication orders including a final volume and concentration of the prescribed dosage of medication, wherein and based on the stored medication orders, the controller calculates the first defined distance that the plunger is moved to draw the first volume of the diluent and causes the plunger to extend the first defined distance, the controller calculates the difference between the final volume and the first volume and instructs the second drug delivery device to deliver to the syringe a volume of medication having a first concentration so as to form the prescribed diluted dosage of medication that has a concentration of medication less than the concentration of the reconstituted medication.
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27. An automated drug preparation system for preparing a prescribed diluted dosage of medication in a syringe comprising:
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a first drug delivery station that includes a first automated drug delivery device that is in fluid communication with a source of a diluent that is for delivery to the syringe; an adjustable plunger extension mechanism that includes a movable component that intimately engages a plunger of the syringe so that a first movement of the movable component is translated into a first extension of the plunger a first defined distance which causes a first volume of the diluent to be drawn into the syringe; a second drug delivery station that includes a second automated drug delivery device at which a commercially prepared vial of medication is located; and a controller that includes stored medication orders including a final volume and concentration of the prescribed diluted dosage of medication, wherein and based on the stored medication orders, the controller calculates the first defined distance that the plunger is moved to draw the first volume of the diluent and causes the plunger to extend the first defined distance, the controller calculates the difference between the final volume and the first volume and instructs the second drug delivery device to deliver to the syringe a volume of medication from the vial of medication so as to form the prescribed diluted dosage of medication that has a concentration of medication less than the concentration of the medication in the vial.
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28. A method for preparing a prescribed diluted dosage of medication in a syringe comprising the steps of:
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providing an automated drug preparation system that includes a drug vial storage station including at least one parent vial and at least one child vial and a drug delivery station that includes an automated drug delivery device that is in fluid communication with a source of diluent; receiving a medication order that includes a final volume and target concentration of the prescribed diluted dosage of medication and processing the medication order and determining whether the diluted dosage of medication can be prepared in a single vial; if the controller determines that the prescribed dosage of medication cannot be prepared in a single vial, a parent vial containing medication is retrieved from the drug vial station and delivered to the drug delivery station; reconstituting the medication in the parent vial by adding a first volume of diluent to form a reconstituted medication having a first concentration that is greater than the target concentration of the prescribed diluted dosage of medication; aspirating a volume of the reconstituted medication and delivering the aspirated volume to one empty child vial; calculating and delivering a second volume of diluent to the volume of reconstituted medication in the child vial such that medication with the target concentration is produced in the child vial; and aspirating the final volume of the medication contained in the child vial and delivering it to the syringe. - View Dependent Claims (29)
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Specification