MOLECULAR CHARACTERIZATION WITH CARBON NANOTUBE CONTROL
First Claim
1. A molecular characterization device comprising:
- a first reservoir containing a liquid solution including a molecule to be characterized;
a second reservoir for containing a liquid solution including a molecule that has been characterized;
a solid state support structure including an aperture having a molecular entrance providing a fluidic connection to the first reservoir and a molecular exit providing a fluidic connection to the second reservoir;
first and second electron transport probes, at least one of the probes comprising a fullerene structure, each of the probes being disposed on the support structure and having a surface abutting a perimeter of the aperture;
a voltage source connected between the probes to apply a voltage bias across the aperture; and
an electrical current monitor connected between the probes for monitoring changes in electron transport between the probes corresponding to translocation of a molecule through the aperture.
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Accused Products
Abstract
There is provided a first reservoir containing a liquid solution including a molecule to be characterized and a second reservoir for containing a liquid solution including a molecule that has been characterized. A solid state support structure is provided including an aperture having a molecular entrance providing a fluidic connection to the first reservoir and a molecular exit providing a fluidic connection to the second reservoir. First and second electron transport probes are each disposed on the support structure with a surface abutting a perimeter of the aperture. At least one of the probes comprises a fullerene structure, e.g., a carbon nanotube. A voltage source is connected between the probes to apply a voltage bias across the aperture. An electrical current monitor is connected between the probes for monitoring changes in electron transport between the probes corresponding to translocation of a molecule through the aperture.
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Citations
66 Claims
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1. A molecular characterization device comprising:
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a first reservoir containing a liquid solution including a molecule to be characterized; a second reservoir for containing a liquid solution including a molecule that has been characterized; a solid state support structure including an aperture having a molecular entrance providing a fluidic connection to the first reservoir and a molecular exit providing a fluidic connection to the second reservoir; first and second electron transport probes, at least one of the probes comprising a fullerene structure, each of the probes being disposed on the support structure and having a surface abutting a perimeter of the aperture; a voltage source connected between the probes to apply a voltage bias across the aperture; and an electrical current monitor connected between the probes for monitoring changes in electron transport between the probes corresponding to translocation of a molecule through the aperture. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32)
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33. A molecular characterization device comprising:
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a first reservoir containing a liquid solution including at least one molecule coupled to a carbon nanotube in a molecule-nanotube complex to be characterized; a second reservoir for containing a liquid solution including a molecule-nanotube complex that has been characterized; a solid state support structure including an aperture having a molecular entrance providing a fluidic connection to the first reservoir and a molecular exit providing a fluidic connection to the second reservoir; an electrical connection to the aperture for detecting translocation of a molecule-nanotube complex through the aperture. - View Dependent Claims (34, 35, 36, 37, 38, 39)
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40. A method for characterization of a molecule comprising:
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translocating a molecule through an aperture in a support structure from a first reservoir containing a liquid solution including the molecule to be characterized to a second reservoir for containing a liquid solution including a molecule that has been characterized; coupling the molecule to a surface of a carbon nanotube; and monitoring changes in electron transport across the aperture, between two electron transport probes which each abut on a perimeter of the aperture, the changes in electron transport corresponding to translocation of the molecule through the aperture. - View Dependent Claims (41, 42, 43, 44, 45, 46, 47, 48, 49, 50)
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51. A method for characterization of a molecule comprising:
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coupling a molecule to a carbon nanotube in a liquid solution to form a molecule-nanotube complex; translocating the coupled molecule-nanotube complex through an aperture in a support structure from a first reservoir containing a liquid solution including the coupled molecule-nanotube complex to be characterized to a second reservoir for containing a liquid solution including a molecule-nanotube complex that has been characterized; and detecting translocation of the molecule-nanotube complex through the aperture. - View Dependent Claims (52, 53, 54)
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55. A method for characterization of a molecule comprising:
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translocating a molecule through an aperture in a support structure from a first reservoir containing a liquid solution including the molecule to be characterized to a second reservoir for containing a liquid solution including a molecule that has been characterized; coupling the molecule to a surface of a carbon nanotube; and monitoring changes in conductance of the nanotube corresponding to translocation of the molecule through the aperture. - View Dependent Claims (56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66)
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Specification