Drug Delivery Apparatus and Method for Automatically Reducing Drug Dosage
2 Assignments
0 Petitions
Accused Products
Abstract
A drug delivery device which includes a fluid drug reservoir, a catheter, a controllable fluid transfer device, e.g., a pump mechanism or valve, and a drug delivery control means. The drug delivery control means comprises a controller, e.g., a microprocessor or microcontroller which is operable to automatically reduce the rate of drug delivery over a certain reduction interval (e.g., multiple days) from an initial dosage value to a final dosage value.
78 Citations
39 Claims
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1-16. -16. (canceled)
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17. An implantable drug delivery device, comprising:
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an implantable housing configured for implantation into a body; a reservoir within the implantable housing; a fluid transfer device within the implantable housing in fluidic communication with the reservoir; and means, carried within the implantable housing, for repeatedly modifying an entire stored delivery profile including at least one delivery rate in response to a single receipt of modification data. - View Dependent Claims (18, 19, 20, 21, 22)
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23. A method of operating an implantable drug delivery device, comprising the step of:
repeatedly modifying a delivery profile that includes a plurality of delivery rates and is stored within the implantable drug delivery device with the implantable drug delivery device in response to a single receipt of wirelessly transmitted modification data. - View Dependent Claims (24, 25, 26, 27, 28, 29)
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30. A method of modifying the dosage of a drug supplied by a drug delivery device that stores a delivery profile including at least one delivery rate and is located entirely within a patient, the method comprising the steps of:
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wirelessly transmitting a final daily dosage value to the drug delivery device located entirely within the patient; wirelessly transmitting a reduction rate or a reduction interval to the drug delivery device located entirely within the patient; and allowing the drug delivery device located entirely within the patient to itself iteratively reduce the at least one delivery rate over the course of a plurality of days as a function of the transmitted final daily dosage value and the transmitted reduction rate or as a function of the transmitted final daily dosage value and the transmitted reduction interval. - View Dependent Claims (31, 32, 33, 34, 35)
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36. A method of operating an implantable drug delivery device, comprising the steps of:
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initiating a dosage reduction mode in response to a single event; and modifying a delivery profile that includes one or more clinically significant delivery rates and is stored within the implantable drug delivery device by reducing the one or more clinically significant delivery rates to one or more lower clinically significant delivery rates with the implantable drug delivery device in response to the initiation of the dosage reduction mode. - View Dependent Claims (37, 38, 39)
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Specification