×

TABLET-IN-TABLET COMPOSITIONS

  • US 20080175908A1
  • Filed: 01/11/2008
  • Published: 07/24/2008
  • Est. Priority Date: 01/12/2007
  • Status: Abandoned Application
First Claim
Patent Images

1. A tablet-in-tablet composition comprising:

  • a) a core tablet comprising;

    one or more estrogens;

    a core filler/diluent component comprising from about 30% to about 85% by weight of said core tablet;

    a core filler/binder component comprising from about 1% to about 30% by weight of said core tablet;

    a core hydrophilic gel-forming polymer component comprising from about 1% to about 40% by weight of said core tablet; and

    optionally, a core lubricant component comprising from about 0.01% to about 2% by weight of said core tablet; and

    b) a compressed outer tablet layer comprising;

    one or more therapeutic agents selected from the group consisting of selective estrogen receptor modulators and progestational agents;

    an outer layer filler/diluent component comprising from about 10% to about 80% by weight of said compressed outer tablet layer;

    an outer layer filler/binder component comprising from about 1% to about 60% by weight of said compressed outer tablet layer;

    an outer layer hydrophilic gel-forming polymer component comprising from about 1% to about 70% by weight of said compressed outer tablet layer;

    optionally, an antioxidant component comprising from about 0.01% to about 4% by weight of said compressed outer tablet layer; and

    optionally, an outer layer lubricant component comprising from about 0.01% to about 2% by weight of said compressed outer tablet layer.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×