Articles having localized molecules disposed thereon and methods of producing same
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Abstract
Methods of producing substrates having selected active chemical regions by employing elements of the substrates in assisting the localization of active chemical groups in desired regions of the substrate. The methods may include optical, chemical and/or mechanical processes for the deposition, removal, activation and/or deactivation of chemical groups in selected regions of the substrate to provide selective active regions of the substrate.
160 Citations
87 Claims
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1-60. -60. (canceled)
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61. A method of selectively immobilizing a molecule of interest on a substrate, comprising:
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providing a substrate having a first surface component and a second surface component where the first and second surface component have different surface characteristics; and selectively coupling the molecule of interest to the first surface component, based upon a difference between the surface characteristics of the first surface component and the surface characteristics of the second surface component. - View Dependent Claims (62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86)
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87. A method of selectively depositing a molecule of interest on selected regions of a substrate, comprising:
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providing a substrate having first and second components, the first component comprising a conductive material and the second component comprising an insulator; and applying an electrical potential to the first component so as to increase or decrease association of a molecule of interest with a surface of the first component.
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Specification