NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME
First Claim
Patent Images
1. A composition, comprising:
- a first agent selected from the group consisting of an oxidative phosphorylation inhibitor, an ionophore, and an adenosine 5′
-monophosphate-activated protein kinase (AMPK) activator;
a second agent that possesses anti-inflammatory activity; and
a third agent that possesses or maintains serotonin activity.
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Abstract
The invention relates to a composition that includes a first agent selected from the group consisting of an oxidative phosphorylation inhibitor, an ionophore, and an adenosine 5′-monophosphate-activated Protein kinase (AMPK) activator; a second agent that possesses anti-inflammatory activity; and a third agent that possesses serotonin activity.
73 Citations
52 Claims
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1. A composition, comprising:
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a first agent selected from the group consisting of an oxidative phosphorylation inhibitor, an ionophore, and an adenosine 5′
-monophosphate-activated protein kinase (AMPK) activator;a second agent that possesses anti-inflammatory activity; and a third agent that possesses or maintains serotonin activity. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A composition, comprising:
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a first agent selected from the group consisting of metformin, phenformin, buformin, ephedrine, thyroxine, salicylanilide, and salicylic acid; a second agent that possesses anti-inflammatory activity; and a third agent that possesses or maintains serotonin activity. - View Dependent Claims (23, 24, 25, 26, 27, 28)
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29. A method for treating metabolic syndrome, comprising administering to a subject in need thereof an effective amount of a composition containing a first agent selected from the group consisting of an oxidative phosphorylation inhibitor, an ionophore, and an AMPK activator;
- a second agent that possesses anti-inflammatory activity; and
a third agent that possesses or maintains serotonin activity. - View Dependent Claims (30, 31, 32)
- a second agent that possesses anti-inflammatory activity; and
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33. A method for treating obesity, comprising administering to a subject in need thereof an effective amount of a composition containing a first agent selected from the group consisting of an oxidative phosphorylation inhibitor, an ionophore, and an AMPK activator;
- a second agent that possesses anti-inflammatory activity; and
a third agent that possesses or maintains serotonin activity. - View Dependent Claims (34, 35, 36)
- a second agent that possesses anti-inflammatory activity; and
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37. A method for treating hypertension, comprising administering to a subject in need thereof an effective amount of a composition containing a first agent selected from the group consisting of an oxidative phosphorylation inhibitor, an ionophore, and an AMPK activator;
- a second agent that possesses anti-inflammatory activity; and
a third agent that possesses or maintains serotonin activity. - View Dependent Claims (38, 39, 40)
- a second agent that possesses anti-inflammatory activity; and
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41. A method for treating diabetes, comprising administering to a subject in need thereof an effective amount of a composition containing a first agent selected from the group consisting of an oxidative phosphorylation inhibitor, an ionophore, and an AMPK activator;
- a second agent that possesses anti-inflammatory activity; and
a third agent that possesses or maintains serotonin activity. - View Dependent Claims (42, 43, 44)
- a second agent that possesses anti-inflammatory activity; and
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45. A method for treating Parkinson'"'"'s disease, comprising administering to a subject in need thereof an effective amount of a composition containing a first agent selected from the group consisting of an oxidative phosphorylation inhibitor, an ionophore, and an AMPK activator;
- a second agent that possesses anti-inflammatory activity; and
a third agent that possesses or maintains serotonin activity. - View Dependent Claims (46, 47, 48)
- a second agent that possesses anti-inflammatory activity; and
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49. A method for treating polycystic ovarian syndrome, comprising administering to a subject in need thereof an effective amount of a composition containing a first agent selected from the group consisting of an oxidative phosphorylation inhibitor, an ionophore, and an AMPK activator;
- a second agent that possesses anti-inflammatory activity; and
a third agent that possesses or maintains serotonin activity. - View Dependent Claims (50, 51, 52)
- a second agent that possesses anti-inflammatory activity; and
Specification