ISCHEMIA DETECTION USING HEART SOUND TIMING
First Claim
1. A device comprising:
- a heart sound sensor configured to produce a heart sound signal representative of a heart sound, the heart sound associated with mechanical cardiovascular activity of a heart of a subject; and
a signal analyzer circuit in electrical communication with the heart sound sensor, wherein the signal analyzer circuit is configured to;
establish a baseline time interval between a first detected physiologic cardiovascular event and at least one second detected physiologic cardiovascular event, wherein at least one of the first and second detected physiologic cardiovascular events includes a heart sound event detected using the heart sound signal; and
determine that an ischemic event occurred when a measured subsequent change from the established baseline time interval occurs with a time constant that is within a specified range of time constants.
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Abstract
A system comprising a heart sound sensor to produce a heart sound signal representative of at least one heart sound. A signal analyzer circuit measures a baseline time interval between a first detected physiologic cardiovascular event and at least one second detected physiologic cardiovascular event. At least one of the first and second detected physiologic cardiovascular events includes a heart sound event obtained from the heart sound signal. The sensor analyzer circuit determines that an ischemic event occurred at least in part by detecting a specified measured subsequent change from the established baseline time interval. Other systems and methods are disclosed.
249 Citations
36 Claims
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1. A device comprising:
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a heart sound sensor configured to produce a heart sound signal representative of a heart sound, the heart sound associated with mechanical cardiovascular activity of a heart of a subject; and a signal analyzer circuit in electrical communication with the heart sound sensor, wherein the signal analyzer circuit is configured to; establish a baseline time interval between a first detected physiologic cardiovascular event and at least one second detected physiologic cardiovascular event, wherein at least one of the first and second detected physiologic cardiovascular events includes a heart sound event detected using the heart sound signal; and determine that an ischemic event occurred when a measured subsequent change from the established baseline time interval occurs with a time constant that is within a specified range of time constants. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A method comprising:
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sensing a heart sound event, the sensing including producing at least one heart sound signal representative of the heart sound event, the heart sound event associated with mechanical cardiovascular activity of a heart of a subject; establishing a baseline time interval between a first detected physiologic cardiovascular event and at least one second detected physiologic cardiovascular event, wherein at least one of the first and second detected physiologic cardiovascular events includes a heart sound event detected from the heart sound signal; and determining that an ischemic event occurred when a measured subsequent change from the established baseline time interval occurs with a time constant that is within a specified range of time constants. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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Specification