METHOD OF PRODUCING A RADIALLY EXPANDABLE PROSTHESIS

• US 20080178459A1
• Filed: 01/29/2008
• Published: 07/31/2008
• Est. Priority Date: 01/29/2007
• Status: Active Grant

• Current Assignee: Cook Medical Technologies, LLC (Cook Group Incorporated)
• Original Assignee: Cook Incorporated (Cook Group Incorporated)
• Inventors: Hoffa, Michael C., Mead, Jason A., DeBruyne, Michael P., Dittman, Jay A., Barr, Aaron P., Nickless, Benjamin
• Granted Patent: US 8,024,851 B2
• Time in Patent Office: Days
• US Class Current: 29/557
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/8483 Barbs
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2250/0068 the pharmaceutical product being in a reservoir
• CPC Class Codes: Y10T 29/49995 Shaping one-piece blank by removing material

Abstract

A method for producing a radially expandable prosthesis by cutting a pattern in a tubular member, which member has an outer diameter at least as great as the expanded diameter of the prosthesis.

Claims

1. A method of producing a radially expandable prosthesis, comprising:

providing a tubular member having an outer diameter;

cutting a pattern in the tubular member to provide a tubular prosthesis where the tubular prosthesis is adapted to have a compressed diameter for endoluminal delivery and an expanded diameter for use upon implantation;

where the tubular member outer diameter is at least as great as the prosthesis expanded diameter.

2. The method of claim 1, where the pattern comprises anchoring members.

3. The method of claim 2, where the anchoring members comprise integral barbs.

4. The method of claim 1, where the pattern comprises notches.

5. The method of claim 1, further comprising forming at least one cavity in the prosthesis.

6. The method of claim 5, where the at least one cavity is at least partially loaded with a therapeutic agent.

7. The method of claim 5, where the at least one cavity is at least partially loaded with a radiopaque material.

8. The method of claim 1, further comprising finishing the prosthesis.

9. The method of claim 8, where the finishing comprises electro-polishing the prosthesis.

10. The method of claim 1, further comprising coating the prosthesis with a therapeutic agent.

11. The method of claim 10, where the therapeutic agent is selected from the group consisting of anti-inflammatory/immunomodulators, antiproliferatives, migration inhibitors/ECM-modulators, and agents that promote healing.

12. The method of claim 11, where the therapeutic agent comprises paclitaxel or a paclitaxel derivative.

13. The method of claim 1, where the tubular member comprises material selected from the group consisting of stainless steel, nitinol, tantalum, a nonmagnetic nickel-cobalt-chromium-molybdenum alloy, platinum, titanium, a suitable biocompatible alloy, a suitable biocompatible material, and a combination thereof.

14. The method of claim 13, where the tubular member material comprises nitinol or stainless steel.

15. A method of producing a radially expandable prosthesis, comprising:

providing a tubular member having an outer diameter;

laser cutting a continuous pattern in the tubular member to provide a tubular prosthesis where the tubular prosthesis is adapted to have a compressed diameter for endoluminal delivery and an expanded diameter for use upon implantation;

where the tubular member outer diameter is at least as great as the prosthesis expanded diameter.

16. The method of claim 15, where the continuous pattern comprises a zigzag shape.

17. The method of claim 16, where the zigzag shape comprises apexes and struts, the apexes comprising a smaller width than the struts.

18. The method of claim 16, where the continuous pattern further comprises integral barbs.

19. The method of claim 16, where the continuous pattern further comprises notches.

20. A method of producing a radially expandable stent, comprising:

providing a tubular member having an outer diameter;

laser cutting a zigzag pattern to provide a zigzag stent comprising apexes and struts;

where the zigzag stent is adapted to have a compressed diameter for endoluminal delivery and an expanded diameter for use upon implantation;

where the apexes have a width less than the struts;

where the struts comprise integral barbs;

where the tubular member outer diameter is at least as great as the expanded diameter of the stent.