MICROPARTICLES
First Claim
Patent Images
1. A method of forming particles, comprising:
- accelerating a first stream comprising a first liquid;
applying a charging voltage of at most 1.5 kV to the first stream; and
vibrating the first stream, to form particles.
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Abstract
A method of forming particles, comprises accelerating a first stream comprising a first liquid, applying a charging voltage of at most 1.5 kV to the first stream, and vibrating the first stream, to form particles.
68 Citations
41 Claims
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1. A method of forming particles, comprising:
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accelerating a first stream comprising a first liquid; applying a charging voltage of at most 1.5 kV to the first stream; and vibrating the first stream, to form particles. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 41)
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25. A method of forming chitosan or alginate particles, comprising:
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accelerating a first stream comprising a solution of chitosan or alginate, applying a charging voltage of at most 1.5 kV to the first stream; vibrating the first stream, to form particles; and maintaining the particles at a pressure of at least 0.1 mm Hg and of at most 760 mm Hg, while heating the particles to a temperature within ±
50°
C. of the boiling point of water at the pressure;wherein the accelerating comprises contacting the first stream with a second stream, and the second stream comprises a hydrophobic liquid. - View Dependent Claims (26, 27, 28, 29, 30)
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31. The method of claim 31, wherein the particles have an average diameter of at least 10 nm to at most 100 μ
- m.
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32. Particles comprising chitosan or alginate having an average diameter of at least 1 μ
- m to at most 100 μ
m, wherein 90% of the particles have a diameter that is within 1 μ
m of an average diameter of the particles. - View Dependent Claims (33, 34, 35, 36)
- m to at most 100 μ
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37. A method of forming gelatin particles, comprising:
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accelerating a first stream comprising an aqueous solution of gelatin, applying a charging voltage of at most 1.5 kV to the first stream; vibrating the first stream, to form particles; and subjecting the particles to a temperature at most 10°
C. above the gelling temperature of the solution of gelatin;wherein the accelerating comprises contacting the first stream with a second stream, and the second stream comprises a hydrophobic liquid. - View Dependent Claims (38, 39, 40)
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Specification