PARALLEL GENOTYPING OF MULTIPLE PATIENT SAMPLES
0 Assignments
0 Petitions
Accused Products
Abstract
The present invention relates to parallel genotyping (or other sample analysis) of multiple patients by direct sample immobilization onto microspheres of an array. The patient beads can then be used in a variety of target analyte analyses.
-
Citations
50 Claims
-
1-26. -26. (canceled)
-
27. A method comprising:
-
a) providing an array composition comprising; i) a substrate with a surface comprising discrete sites; and ii) a population of microspheres comprising at least a first and a second microsphere, wherein a plurality of different target analytes from a first individual are covalently attached to said first microsphere, wherein a plurality of different target analytes from a second individual are covalently attached to said second microsphere, and wherein said microspheres are distributed at said discrete sites; b) contacting said array composition with a first set of readout probes; and c) detecting the presence of a first target analyte. - View Dependent Claims (28, 29, 30, 31, 32, 33, 34, 35, 36)
-
-
38. A method comprising:
-
a) providing an array composition comprising; i) a substrate with a surface comprising discrete sites; and ii) a population of microspheres comprising at least a first and a second microsphere, wherein a plurality of different target analytes from a first individual are attached to said first microsphere via receptor-ligand interactions, wherein a plurality of different target analytes from a second individual are attached to said second microsphere via receptor-ligand interactions, and wherein said microspheres are distributed at said discrete sites; b) contacting said array composition with a first set of readout probes; and c) detecting the presence of a first target analyte. - View Dependent Claims (39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50)
-
Specification