ANTI-NGF ANTIBODIES AND METHODS USING SAME
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Abstract
The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
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Citations
100 Claims
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1-86. -86. (canceled)
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87. A method for treating osteoarthritis pain in an individual comprising administering an effective amount of an anti-NGF antagonist antibody, wherein said antibody comprises a heavy chain variable region comprising:
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(a) a CDR1 region shown in SEQ ID NO;
3;(b) a CDR2 region shown in SEQ ID NO;
4; and(c) a CDR3 region shown in SEQ ID NO;
5;and wherein said antibody further comprises a light chain variable region comprising; (d) a CDR1 region shown in SEQ ID NO;
6;(e) a CDR2 region shown in SEQ ID NO;
7; and(f) a CDR3 region shown in SEQ ID NO;
8.- View Dependent Claims (88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100)
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Specification