METHOD FOR FOSTERING BONE FORMATION AND PRESERVATION
First Claim
1. A kit for fostering bone formation in at least one targeted bone of a subject in need of said bone formation, said kit comprising:
- (a) at least one container having therein at least one bone anabolic agent; and
(b) a mechanical alteration device for altering contents of a bone marrow cavity in at least one said targeted bone.
3 Assignments
0 Petitions
Accused Products
Abstract
A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.
-
Citations
10 Claims
-
1. A kit for fostering bone formation in at least one targeted bone of a subject in need of said bone formation, said kit comprising:
-
(a) at least one container having therein at least one bone anabolic agent; and (b) a mechanical alteration device for altering contents of a bone marrow cavity in at least one said targeted bone. - View Dependent Claims (2, 3, 4, 5, 6, 7)
-
-
8. A kit for fostering bone formation in at least one targeted bone in a subject in need of said bone formation, said kit comprising:
-
(a) at least one container having therein at least one antiresorptive agent; and (b) a mechanical alteration device for altering contents of a bone marrow cavity in at least one said targeted bone. - View Dependent Claims (9, 10)
-
Specification