PROSTHESIS FOR TREATING VASCULAR BIFURCATIONS

• US 20080183269A2
• Filed: 06/30/2006
• Published: 07/31/2008
• Est. Priority Date: 04/14/2003
• Status: Active Grant

• Current Assignee: Poseidon Medical Inc.
• Original Assignee: Tryton Medical, Inc.
• Inventors: Kaplan, Aaron, Davis, H. Richard
• Granted Patent: US 8,672,994 B2
• Time in Patent Office: Days
• US Class Current: 623/1.11
• CPC Class Codes: A61F 2/856 Single tubular stent with a side portal passage
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2/954 for placing stents or stent-grafts in a bifurcation
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2/97 the outer sleeve being splittable
• CPC Class Codes: A61F 2002/821 Ostial stents
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91516 the meander having a change in frequency along the band
• CPC Class Codes: A61F 2002/91525 within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
• CPC Class Codes: A61F 2002/91533 characterised by the phase between adjacent bands
• CPC Class Codes: A61F 2002/9155 Adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2002/91575 connected peak to trough
• CPC Class Codes: A61F 2002/9583 Means for holding the stent on the balloon, e.g. using protrusions, adhesives or an outer sleeve
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61M 25/1002 characterised by balloon shape A61M25/1006, A61M25/1009 take precedence

Abstract

A stepped balloon catheter prosthesis deployment system is disclosed for placement of a prosthesis across an Os opening from a main body lumen to a branch body lumen. The prosthesis comprises a radially expansible support at one end, a circumferentially extending link at the other end and at least one frond extending axially therebetween. The prosthesis is configured to be deployed from a stepped diameter balloon with the support in the branch body lumen, with the circumferentially extending link in the main lumen and the frond extendable across the Os.

Claims

1-13. -13. (canceled)

14. A prosthesis for placement at an opening from a main body lumen to a branch body lumen, the prosthesis comprising:

a radially expansible support, the support configured to be deployed in at least a portion of the branch body lumen;

at least one frond extending from an end of the support and configured to be positioned across the Os and into the main body lumen; and

at least one circumferential link connected to the frond, the circumferential link spaced axially apart from the support.

15. The prosthesis as in claim 14, wherein the circumferential link is expandable from a first, reduced diameter to a second, enlarged diameter.

16. The prosthesis as in claim 14, wherein the at least one frond includes at least three fronds.

17. The prosthesis as in claim 14, wherein the at least one frond comprises a helical configuration.

18. The prosthesis as in claim 17, comprising a plurality of helical fronds.

19. The prosthesis as in claim 14, wherein at least a portion of the frond comprises a lubricous coating.

20. The prosthesis as in claim 14, wherein the support is on a first end of the frond, and the circumferential link is on a second end of the frond.

21. The prosthesis as in claim 14, wherein the circumferential link is radiopaque.

22. The prosthesis as in claim 21, wherein the circumferential link has a greater radiopacity than the frond.

23. The prosthesis as in claim 14, comprising an endothelial cell ingrowth surface.

24. The prosthesis as in claim 14, comprising a non thrombogenic surface.

30. The prosthesis as in claim 14, wherein the at least one frond includes at least three fronds.

31. The prosthesis as in claim 14, wherein the at least one frond comprises a helical configuration.

32. The prosthesis as in claim 31, comprising a plurality of helical fronds.

33. The prosthesis as in claim 14, wherein at least a portion of the at least one frond comprises a lubricous coating.

34. The prosthesis as in claim 14, comprising an endothelial cell ingrowth surface.

35. The prosthesis as in claim 14, comprising a non thrombogenic surface.

36. The prosthesis as in claim 14, wherein the at least one frond comprises a plurality of fronds and wherein the circumferential link connects to each of the plurality of fronds.

37. The prosthesis as in claim 36, wherein at least a portion of the radially expansible support comprises a drug coating, and at least a portion of the fronds and the circumferential link are without a drug coating.

38. The prosthesis as in claim 37, wherein the drug coating is configured to produce at least one of a controlled drug release rate, a constant drug release rate, bi-modal drug release rate or a controlled concentration of drug proximate a target vessel wall.

39. The prosthesis as in claim 37, wherein the drug is one of an anti-cell prolifertive, anti cell migration, anti-neo plastic, anti inflammatory drug.

40. The prosthesis as in claim 37, wherein the drug is configured to reduce an incidence or amount of restensosis.

41. The prosthesis as in claim 37, wherein the drug coating includes a first coating and a second coating.

42. The prosthesis as in claim 41, wherein the first coating is configured to produce a first drug release rate and the second coating is configured to produce a second drug release rate.

43. The prosthesis as in claim 36, wherein the circumferential link is expandable from a first, reduced diameter to a second, enlarged diameter.

44. The prosthesis as in claim 36, wherein the support is on a first end of at least one of the fronds, and the circumferential link is on a second end of at least one of the fronds.

45. The prosthesis as in claim 14, wherein the circumferential link is radiopaque.

46. The prosthesis as in claim 14, wherein the circumferential link has a greater radiopacity than the at least one frond.

47. The prosthesis of claim 14, wherein the prosthesis includes a drug incorporated into a polymer matrix.

48. The prosthesis of claim 14, wherein the prosthesis includes a laminate structure and a drug incorporated into the laminate structure.

49. The prosthesis of claim 48, wherein the laminate structure includes a base layer and a top layer, the drug being incorporated into at least one of the top layer and the base layer.

50. The prosthesis of claim 14, wherein the prosthesis includes one or more reservoirs configured to be loaded with a drug.

51. The prosthesis of claim 50, wherein the prosthesis includes one or more drugs in the one or more reservoirs.

25-29. -29. (canceled)