Shaped load-bearing osteoimplant and methods of making same
First Claim
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1. A load-bearing osteoimplant comprising a shaped coherent mass of bone particles possessing a bulk density of greater than about 0.7 g/cm3.
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Abstract
A load-bearing osteoimplant which comprises a shaped, coherent aggregate of bone particles.
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Citations
44 Claims
- 1. A load-bearing osteoimplant comprising a shaped coherent mass of bone particles possessing a bulk density of greater than about 0.7 g/cm3.
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2. A load-bearing osteoimplant comprising a shaped coherent mass of bone particles possessing a wet compressive strength of at least about 3 MPa.
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3. A method for making a load-bearing osteoimplant which comprises:
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a) providing an aggregate containing bone particles and, optionally, one or more optional components selected from the group consisting of binder, filler, plasticizer, wetting agent, surface active agent, biostatic/biocidal agent, bioactive substance, reinforcing material and reinforcing structure; and
,b) shaping the aggregate into a coherent mass in at least one shaping operation to provide a shaped composite having an initial configuration for subsequent shaping into a desired osteoimplant or a final configuration corresponding to that of the osteoimplant. - View Dependent Claims (4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
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- 29. An integral implant insertion instrument and implant comprising an implant insertion instrument portion integrally attached to an implant portion by a weakened, break-away connection such that on insertion of the implant portion at the implantation site, the implant insertion instrument portion is separated from the implant portion by a breaking-away force applied thereto, the implant portion being a load-bearing osteoimplant comprising a shaped, coherent mass of bone particles.
- 38. A load-bearing osteoimplant comprising a shaped, coherent mass of bone particles possessing a bulk density of greater than about 0.7 g/cm3 and a wet compressive strength of at least about 3 MPa, wherein the bone particles comprise a combination of nondemineralized and demineralized bone.
Specification