Antimicrobial And Antiviral Polymeric Master Batch, Processes For Producing Polymeric Material Therefrom And Products Produced Therefrom

• US 20080193496A1
• Filed: 03/12/2006
• Published: 08/14/2008
• Est. Priority Date: 03/21/2005
• Status: Abandoned Application

• Current Assignee: The Cupron Corporation
• Original Assignee: The Cupron Corporation
• Inventors: Gabbay, Jeffrey
• Application Number:
  US11/908,771
• Publication Number:
  US 20080193496A1
• Time in Patent Office: Days
• US Class Current: 424/404
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/10 Macromolecular compounds
• CPC Class Codes: A01N 25/34 Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
• CPC Class Codes: A01N 59/20 Copper
• CPC Class Codes: A61B 2017/00889 antimicrobial, disinfectant
• CPC Class Codes: A61B 42/00 Surgical gloves; Finger-stalls specially adapted for surgery; Devices for handling or treatment thereof
• CPC Class Codes: A61B 46/40 Drape material, e.g. laminates; Manufacture thereof
• CPC Class Codes: A61F 2013/49098 Other Details not otherwise provided of the absorbent articles specially adapted to be worn around the waist
• CPC Class Codes: A61L 2300/102 Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61L 29/126 having a macromolecular matrix
• CPC Class Codes: A61L 29/16 Biologically active materials, e.g. therapeutic substances A61L29/048 takes precedence
• CPC Class Codes: A61L 31/128 containing other specific inorganic fillers not covered by A61L31/126 or A61L31/127
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence
• CPC Class Codes: C08J 2323/02 not modified by chemical after treatment
• CPC Class Codes: C08J 2323/06 Polyethene
• CPC Class Codes: C08J 2323/08 Copolymers of ethene C08J2323/16 takes precedence
• CPC Class Codes: C08J 2323/12 Polypropene
• CPC Class Codes: C08J 2323/14 Copolymers of propene C08J2323/16 takes precedence
• CPC Class Codes: C08J 2323/20 having four to nine carbon atoms
• CPC Class Codes: C08J 2327/06 : Homopolymers or copolymers of vinyl chloride
• CPC Class Codes: C08J 2327/18 : Homopolymers or copolymers of tetrafluoroethylene
• CPC Class Codes: C08J 2333/00 : Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
• CPC Class Codes: C08J 2367/00 : Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain of polyester-amides C08J2377/12; of polyester-imides C08J2379/08; Derivatives of such polymers
• CPC Class Codes: C08J 2367/04 : Polyesters derived from hydroxy carboxylic acids, e.g. lactones C08J2367/06 takes precedence
• CPC Class Codes: C08J 2375/04 : Polyurethanes
• CPC Class Codes: C08J 2377/00 : Characterised by the use of polyamides obtained by reactions forming a carboxylic amide link in the main chain of polyhydrazides C08J2379/06; of polyamide-imides or polyamide acids C08J2379/08; Derivatives of such polymers
• CPC Class Codes: C08J 2400/22 : Thermoplastic resins
• CPC Class Codes: C08J 2491/06 : Waxes
• CPC Class Codes: C08J 3/201 : Pre-melted polymers
• CPC Class Codes: C08J 3/22 : using masterbatch techniques
• CPC Class Codes: C08K 2003/2248 : of copper
• CPC Class Codes: C08K 3/22 : of metals
• CPC Class Codes: C08K 5/0008 : Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
• CPC Class Codes: C08L 23/06 : Polyethene
• CPC Class Codes: C08L 67/02 : Polyesters derived from dicarboxylic acids and dihydroxy compounds C08L67/06 takes precedence
• CPC Class Codes: C08L 67/04 : Polyesters derived from hydroxycarboxylic acids, e.g. lactones C08L67/06 takes precedence
• CPC Class Codes: C08L 91/06 : Waxes
• CPC Class Codes: D01F 1/10 : Other agents for modifying properties

Abstract

A polymeric master batch for preparing an antimicrobal and antifungal and antiviral polymeric material comprising a slurry of thermoplastic resin, an antimicrobal and antifungal and antiviral agent consisting essentially of water insoluble particles of ionic copper oxide, a polymeric wax and an agent for occupying the charge of the ionic copper oxide.

Claims

1. A polymeric master batch for preparing an antimicrobal and antifungal and antiviral polymeric material comprising a slurry of thermoplastic resin, an antimicrobal and antifungal and antiviral agent consisting essentially of water insoluble particles of ionic copper oxide, a polymeric wax and an agent for occupying the charge of said ionic copper oxide.

2. A polymeric master batch according to claim 1, comprising between about 4% and 83% of a thermoplastic resin, about 10%-60% on a weight basis of water insoluble particles of ionic copper oxide, between about 1% and 30% of a polymeric wax, and between about 1% and 6% of an agent for occupying the charge of said ionic copper oxide.

3. A polymeric master batch according to claim 1, wherein said agent is selected from the group consisting of a chelating agent, and a metal deactivating agent.

4. A polymeric master batch according to claim 1, wherein said agent is selected from the group consisting of a metal deactivating phosphite, a phenolic antioxidant, potassium iodide, potassium bromide, calcium stearate, zinc stearate, aluminium stearate, tertiary chain extenders and combinations thereof.

5. A polymeric master batch according to claim 1, wherein said agent is a metal deactivator.

6. A polymeric master batch according to claim 1, wherein said agent is a phenolic antioxidant.

7. A polymeric master batch according to claim 1, wherein said thermoplastic resin is selected from the group consisting of a polyester, a polyolefin, a nylon, a polyurethane, polytetrafluoroethylene, polypropylene, polyethylene, polyvinyl chloride, an acrylic, polybutylene, polylactic acid, PTT, a silicon and mixtures thereof.

8. A polymeric master batch according to claim 1 wherein said polymeric wax is selected from the group consisting of polyethylene wax, oxidized polyethylene wax, ionomer wax, malaeic anhydride wax, and mixtures thereof.

22. An antimicrobial and antiviral polymeric material according to claim 1 wherein said thermoplastic resin is a single polymeric component.

33. The use of a polymeric material produced from a master batch according to claim 1, for inhibition of HIV-1 proliferation.

34. The use of a polymeric material produced from a master batch according to claim 1 for neutralizing infectious viruses.

35. Condoms whenever produced from a master batch according to claim 1.

36. Catheters whenever produced from a master batch according to claim 1.

37. Gloves whenever produced from a master batch according to claim 1.

38. Non-woven fabrics whenever produced from a master batch according to claim 1.

40. Disposable hospital and operating theatre products for combating viral infections, said products incorporating fibers produced from a master batch according to claim 1, wherein said fibers are effective for the inactivation of viruses and fluids brought in contact therewith.

43. A master batch according to claim 1 further comprising one or more pigments.

44. A device for the inactivation of a virus comprising a housing delimiting a fluid passageway, said passageway being provided with a filtering material including polymeric fibers comprising an antimicrobial, antifungal and antiviral agent consisting essentially of discreet water insoluble ionic copper oxide particles that release Cu⁺⁺ incorporated therein with a portion of said particles being exposed and protruding from surfaces thereof, wherein said fibers are produced from a master batch according to claim 1.

9. A process for preparing an antimicrobial, antifungal and antiviral polymeric material, comprising preparing a slurry of a thermoplastic resin, introducing a powder consisting essentially of water insoluble cationic copper oxides and dispersing the same in said slurry in combination with a polymeric wax and an agent for occupying the charge of said ionic copper oxide and then extruding said slurry to form a polymeric material wherein discreet water insoluble copper oxide particles that release Cu⁺⁺ are formed and incorporated therein with a portion of said particles being exposed and protruding from surfaces thereof.

10. A process according to claim 9, wherein said combination of ingredients is carried out with high intensity mixing for a period of about 2-10 minutes and at a temperature of between 80°

C. and 150°

C.

11. A process according to claim 9 comprising combining between about 4% and 83% of a thermoplastic resin, about 10%-60% on a weight basis of water insoluble particles of ionic copper oxide, between about 1% and 30% of a polymeric wax, and between about 1% and 6% of an agent for occupying the charge of said ionic copper oxide.

12. A process according to claim 9 wherein said agent is a chelating agent.

13. A process according to claim 9 wherein said agent is selected from the group consisting of a metal deactivating phosphyte, a phenolic antioxidant, potassium iodide, potassium bromide, calcium stearate, zinc stearate, aluminium stearate, tertiary chain extenders and combinations thereof.

14. A process according to claim 9, wherein said agent is a metal deactivator.

15. A process according to claim 9, wherein said agent is a phenolic antioxidant.

16. A process according to claim 9, wherein said thermoplastic resin is selected from the group consisting of a polyester, a polyolefin, a nylon, a polyurethane, polytetrafluoroethylene, polypropylene, polyethylene, polyvinyl chloride, an acrylic, polybutylene, polylactic acid, PTT, a silicon and mixtures thereof.

17. A process according to claim 9 wherein said polymeric wax is selected from the group consisting of consisting of homopolymers and co-polymers of polyethylene, polypropylene and lonomer waxes, and mixtures thereof.

18. An antimicrobial, antifungal and antiviral polymeric material whenever produced according to the process of claim 9, said material being in the form of a fiber, a yarn, or a sheet and comprising an antimicrobial, antifungal and antiviral agent consisting essentially of discreet water insoluble ionic copper oxide particles that release Cu⁺⁺ incorporated therein with a portion of said particles being exposed and protruding from surfaces thereof.

19. An antimicrobial and antiviral polymeric material according to claim 18, wherein the ionic copper comprises a mixture of CuO and Cu₂O.

20. An antimicrobial and antiviral polymeric material according to claim 18, wherein said particles are of a size of between 1 and 10 microns.

21. An antimicrobial and antiviral polymeric material according to claim 18 wherein said particles are present in an amount of between 0.25 and 5% of the polymer weight.

23. An antimicrobial and antiviral polymeric material according to claim 18, wherein said polymeric material is manufactured in the form of a short staple fiber.

24. A blended yarn incorporating fibers produced according to the process of claim 18.

25. A bi-component yarn wherein at least one of the components is an antimicrobial and antiviral polymeric material produced according to the process of claim 18.

26. An article of clothing incorporating a yarn which includes an antimicrobial and antiviral polymeric material produced according to the process of claim 18.

27. A wrapping material comprising an antimicrobial polymeric material produced according to the process of claim 18.

28. A carpet having an antimicrobial and antiviral polymeric material produced according to the process of claim 18 incorporated into a backing layer thereof.

29. A non-woven molded product having an antimicrobial and antiviral polymeric material produced according to the process of claim 18 incorporated therein.

30. A non-woven molded product according to claim 29 wherein said product is air permeable.

31. A non-woven molded product according to claim 29 wherein said product is liquid permeable.

32. Textile fabrics for combating nosocomial infections in health care facilities, said fabric incorporating a fiber, a yarn, or a sheet and comprising an antimicrobial and antiviral agent consisting essentially of discreet water insoluble copper oxide particles that release Cu⁺⁺ incorporated therein with a portion of said particles being exposed and protruding from surfaces thereof whenever produced according to the process of claim 18.

39. Disposable diapers incorporating a non-woven fabric according to claim 39.

41. Disposable hospital and operating theatre products according to claim 41 wherein said products are selected from the group consisting of disposable scrubs, barriers, clothing, masks, shoe covers and caps.

42. Disposable hospital and operating theatre products according to claim 41 wherein said fibers are disposed in said products as randomly scattered fibers in a non-woven textile.

45. A device according to claim 45, wherein said discreet ionic water insoluble copper particles are incorporated in fibers in a non-woven fabric.

46. A device according to claim 45 for inactivating a virus found in cells in body fluids.