Magnetic Stimulating Circuit For Nervous Centralis System Apparatus, Purpose, and Method Thereof

• US 20080200749A1
• Filed: 06/12/2006
• Published: 08/21/2008
• Est. Priority Date: 06/15/2005
• Status: Active Grant

• Current Assignee: Yunfeng Zheng
• Original Assignee: Yunfeng Zheng
• Inventors: Xu, Lin, Wang, Jiang, Zheng, Yunfeng
• Granted Patent: US 8,172,742 B2
• Time in Patent Office: Days
• US Class Current: 600/13
• CPC Class Codes: A61N 2/006 for magnetic stimulation of nerve tissue
• CPC Class Codes: A61N 2/02 using magnetic fields produced by coils, including single turn loops or electromagnets A61N2/12 takes precedence

Abstract

A magnetic stimulation apparatus for central nervous system and circuit thereof and use of the apparatus and method of using the apparatus are shown. Controlling circuit design and outputting wave form signal to a drive power supply circuit enables the drive power supply circuit to output current of corresponding wave form to coils, and by means of the design of the shape, number of turns, size, interval of the coils, generates within a certain region inside the coils a desired time-variant magnetic field which is then applied to the brain of an animal or a human being so that the central nervous system can receive a wide area synergy magnetic stimulation with a precise wave form, high frequency or a combination of a plurality of frequency components, thus achieving the treatment of nervous and psychiatric diseases or brain function improvement in combination with behavior guidance, thought guidance, or psychological guidance.

Claims

1. A magnetic stimulation circuit for central nervous system, comprising:

a control circuit, a drive power supply circuit and coils that are sequentially connected, characterized in that the drive power supply circuit comprises a drive circuit, a detection circuit and a main circuit, both the drive circuit and the detection circuit are connected to the control circuit and the main circuit respectively, and the coils are connected to the main circuit.

2. The magnetic stimulation circuit for central nervous system of claim 1, wherein the main circuit comprises a converting circuit for controlling currents in the coils to flow in the same or opposite direction.

3. The magnetic stimulation circuit for central nervous system of claim 1, wherein the main circuit comprises at least one insulated gate bipolar transistor and the control circuit generates a PWM signal which is used by the drive circuit to drive the insulated gate bipolar transistor in the main circuit to output a time-variant current to the coils which then generate a desired time-variant magnetic field

4. The magnetic stimulation circuit for central nervous system of claim 3, wherein the insulated gate bipolar transistor is replaced by other fill-controlled power semiconductor devices, and the drive circuit is subject to corresponding modifications according to technical features of the replacement devices.

5. The magnetic stimulation circuit for central nervous system of claim 2, wherein the control circuit comprises a Digital Signal Processing (DSP) chip functioning as a main control chip, the drive circuit comprises an optical coupler which is adapted to transfer a control signal sent from the control circuit to the main circuit, and the control circuit controls the drive circuit and the main circuit for the coils to generate a desired magnetic field, and the converting circuit comprises at least one relay.

6. A magnetic stimulation apparatus for central nervous system, comprising a magnetic stimulation circuit, wherein the magnetic stimulation circuit comprises a control circuit, a drive power supply circuit and coils that are sequentially connected, characterized in that the drive power supply circuit comprises a drive circuit, a detection circuit and a main circuit, both the drive circuit and the detection circuit are connected to the control circuit and the main circuit respectively, and the coils are connected to the main circuit.

7. The magnetic stimulation apparatus for central nervous system of claim 6, wherein the coils comprise at least a coaxial, parallel, and symmetrically disposed identical coil pair, with currents in the coil pair being synchronous in time and identical in intensity, the main circuit comprises a converting circuit for controlling the currents in the coil pair to flow in the same or opposite direction.

8. The magnetic stimulation apparatus for central nervous system of claim 6, wherein the main circuit comprises at least one insulated gate bipolar transistor and the control circuit generates a PWM signal which is used by the drive circuit to drive the insulated gate bipolar transistor in the main circuit to output a time-variant current to the coils which then generate a desired time-variant magnetic field.

9. The magnetic stimulation apparatus for central nervous system of claim 8, wherein the insulated gate bipolar transistor is replaced by other full-controlled power semiconductor devices, and the drive circuit is subject to corresponding modifications according to technical features of the replacement devices.

10. The magnetic stimulation apparatus for central nervous system of claim 7, wherein the control circuit comprises a DSP chip functioning as a main control chip, the drive circuit comprises an optical coupler which is adapted to transfer a control signal sent from the control circuit to the main circuit, and the control circuit controls the drive circuit and the main circuit for the coils to generate a desired magnetic field, and the converting circuit comprises at least one relay.

11. Use of a magnetic stimulation apparatus for central nervous system, characterized by treating central nervous system disease or psychiatric disease or improving brain function through selecting a time-variant magnetic field having appropriate parameters to stimulate entire brain of an animal or a human being.

12. The use of a magnetic stimulation apparatus for central nervous system of claim 11, wherein the appropriate parameters comprise at least parameters of wave form, frequency and peak value intensity of current relating to the coil in the apparatus, and wave form, frequency and peak value intensity of corresponding induced magnetic field.

13. The use of a magnetic stimulation apparatus for central nervous system of claim 11, wherein the appropriate parameters further comprise intra-train frequency and inter-train frequency in the case of pulse train magnetic stimulation.

14. The use of a magnetic stimulation apparatus for central nervous system of claim 11, wherein curative effect of the treatment of central nervous system disease or psychiatric disease is improved by introducing behavior guidance, thought guidance, or psychological guidance prior to, in the middle of, or after the magnetic stimulation.

15. The use of a magnetic stimulation apparatus for central nervous system of claim 11, wherein magnetic stimulation having appropriate parameters is applied to the entire brain for an appropriate period, and in the middle of or after the magnetic stimulation, behavior guidance or thought guidance or psychological guidance is performed on those who are receiving or those who have received the magnetic stimulation.

16. The use of a magnetic stimulation apparatus for central nervous system of claim 11, wherein, those who are to receive magnetic stimulation are subject to behavior guidance, thought guidance, or psychological guidance prior to the magnetic stimulation, magnetic stimulation having appropriate parameters is then applied to the entire brain for an appropriate period, and after the magnetic stimulation, those who have received the magnetic stimulation are subject to behavior guidance, thought guidance, or psychological guidance.

17. The use of a magnetic stimulation apparatus for central nervous system of claim 11, wherein the disease is one of the following:

depression, anxiety disorder, insomnia, chronic pain, post-traumatic stress disorder (PTSD), drug or alcohol dependence and addiction, psychic dependence on abnormal behavior, attention deficit, affective or mood disorder, schizophrenia, Parkinson'"'"'s disease, neurodegenerative disease, dementia and nerve injury.

18. The use of a magnetic stimulation apparatus for central nervous system of claim 11, wherein the brain function is learning and memory ability, cognitive ability, or anti psychological stress ability.

19. A method of controlling a magnetic stimulation apparatus for central nervous system with the apparatus being adapted to treat central nervous system disease or psychiatric disease or improving brain function, characterized by electrifying coils through controlling magnetic stimulation circuit to apply a time-variant magnetic field to an objective region, wherein magnetic induction of the magnetic field has a gradient smaller than 100 Gs/cm, and the objective region has a scope matching head size of an animal or a human being.

20. The method of controlling a magnetic stimulation apparatus for central nervous system of claim 19, wherein the magnetic induction of the magnetic field has a peak value smaller than 0.1 T.

21. The method of controlling a magnetic stimulation apparatus for central nervous system of claim 19, wherein during the process of the magnetic stimulation, the magnetic field is of one wave form or a combination of at least two wave forms, and the time-variant magnetic field is within a frequency range of 0.5 Hz to 2000 Hz.