ANALYTE SENSOR
First Claim
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1. A system for continuous measurement of a glucose concentration, the system comprising:
- a continuous glucose sensor configured to generate a signal associated with an in vivo glucose concentration in a host'"'"'s circulatory system; and
a flow control device configured to intermittently meter a reference solution across the continuous glucose sensor.
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Abstract
Systems and methods of use for continuous analyte measurement of a host'"'"'s vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host'"'"'s circulatory system.
849 Citations
30 Claims
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1. A system for continuous measurement of a glucose concentration, the system comprising:
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a continuous glucose sensor configured to generate a signal associated with an in vivo glucose concentration in a host'"'"'s circulatory system; and a flow control device configured to intermittently meter a reference solution across the continuous glucose sensor. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 10, 11)
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9. The system of 1, wherein the reference solution comprises glucose.
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12. A system for continuous measurement of a glucose concentration, the system comprising:
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a continuous glucose sensor comprising a first working electrode and a second working electrode, wherein the continuous glucose sensor is located at least one of in a vascular access device and on a vascular access device in fluid communication with a host'"'"'s circulatory system; and a flow control device configured to intermittently meter a glucose reference solution across the continuous glucose sensor such that the continuous glucose sensor intermittently measures the glucose concentration of the reference solution, and wherein the system is configured to calibrate the continuous glucose sensor using the measured glucose concentration of the reference solution. - View Dependent Claims (13, 14, 15, 16, 17)
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18. A system for continuous measurement of an analyte concentration, the system comprising:
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a continuous analyte sensor located at least one of in a vascular access device and on a vascular access device in fluid communication with a host'"'"'s circulatory system; and a flow control device configured to intermittently meter a reference solution across the continuous analyte sensor such that the continuous analyte sensor is in continuous contact with either the reference solution or a blood sample from the host'"'"'s circulatory system, wherein the flow control device is configured such that the continuous glucose sensor is in contact with the glucose reference solution at least about 50% of the time during a sensor session. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification