SETTING MADATORY MECHANICAL VENTILATION PARAMETERS BASED ON PATIENT PHYSIOLOGY

• US 20080202524A1
• Filed: 02/28/2007
• Published: 08/28/2008
• Est. Priority Date: 02/23/2007
• Status: Abandoned Application

• Current Assignee: General Electric Company
• Original Assignee: General Electric Company
• Inventors: Tham, Robert Quinyew, Mitton, Michael Paul, Choncholas, Gary James
• Application Number:
  US11/680,399
• Publication Number:
  US 20080202524A1
• Time in Patent Office: Days
• US Class Current: 128/204.22
• CPC Class Codes: A61M 16/0078 Breathing bags
• CPC Class Codes: A61M 16/01 specially adapted for anaesthetising A61M16/104, A61M16/18 take precedence
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/104 specially adapted for anaesthetics A61M16/18 takes precedence
• CPC Class Codes: A61M 16/22 Carbon dioxide-absorbing devices ; Other means for removing carbon dioxidecartridges with absorbing substances for respiratory apparatus A62B19/00
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: A61M 2016/0036 in the breathing tube and used in both inspiratory and expiratory phase
• CPC Class Codes: A61M 2016/1025 the O2 concentration
• CPC Class Codes: A61M 2016/103 the CO2 concentration
• CPC Class Codes: A61M 2016/1035 the anaesthetic agent concentration
• CPC Class Codes: A61M 2202/0208 Oxygen
• CPC Class Codes: A61M 2202/0225 Carbon oxides, e.g. Carbon dioxide
• CPC Class Codes: A61M 2202/0283 Nitrous oxide (N2O)
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2230/005 Parameter used as control input for the apparatus
• CPC Class Codes: A61M 2230/06 Heartbeat rate only
• CPC Class Codes: A61M 2230/202 partial carbon oxide pressure, e.g. partial dioxide pressure (P-CO2)
• CPC Class Codes: A61M 2230/205 partial oxygen pressure (P-O2)
• CPC Class Codes: A61M 2230/30 : Blood pressure A61M2230/04 takes precedence
• CPC Class Codes: A61M 2230/42 : Rate
• CPC Class Codes: A61M 2230/43 : Composition of exhalation
• CPC Class Codes: A61M 2230/432 : partial CO2 pressure (P-CO2)
• CPC Class Codes: A61M 2230/435 : partial O2 pressure (P-O2)
• CPC Class Codes: A61M 2230/437 : the anaesthetic agent concentration
• CPC Class Codes: A61M 2230/50 : Temperature

Abstract

A method of setting a subject'"'"'s breath size in controlled mechanical ventilation, comprising varying a subject'"'"'s tidal volumes and/or inspiratory pressures for a predetermined inspiratory time and predetermined expiratory time; determining end tidal gas concentrations associated with said tidal volumes and/or inspiratory pressures; and curve-fitting a relationship between said tidal volumes and/or inspiratory pressures and said end tidal gas concentrations.

Claims

1. A method of setting a subject'"'"'s breath size in controlled mechanical ventilation, comprising:

varying a subject'"'"'s tidal volumes for a predetermined inspiratory time and predetermined expiratory time;

determining end tidal gas concentrations associated with said tidal volumes; and

curve-fitting a relationship between said tidal volumes and said end tidal gas concentrations.

2. The method of claim 1, wherein said gas concentrations include one or more gases exhaled by said subject.

3. The method of claim 2, wherein at least one of said gases includes carbon dioxide.

4. The method of claim 2, wherein at least one of said gases includes oxygen.

5. The method of claim 2, wherein at least one of said gases includes nitrous oxide.

6. The method of claim 2, wherein at least one of said gases includes inhaled anesthetic agent.

7. The method of claim 1, further comprising:

determining a desired tidal volume for said subject based on a desired end tidal gas concentration and said relationship.

8. The method of claim 1, further comprising:

displaying said relationship; and

determining a desired tidal volume for said subject based on a desired end tidal gas concentration and said display.

9. A method of setting a subject'"'"'s breath size in controlled mechanical ventilation, comprising:

varying a subject'"'"'s tidal volumes for a predetermined inspiratory time and predetermined expiratory time;

determining end tidal gas concentrations associated with said tidal volumes;

curve-fitting a first relationship between said tidal volumes and said end tidal gas concentrations; and

establishing a second relationship between said tidal volumes and inspiratory pressures.

10. The method 9, further comprising:

determining a desired inspiratory pressure for said subject based on a desired end tidal gas concentration, said first relationship, and said second relationship.

11. A method of setting a subject'"'"'s breath size in controlled mechanical ventilation, comprising:

varying a subject'"'"'s inspiratory pressures for a predetermined inspiratory time and predetermined expiratory time;

determining end tidal gas concentrations associated with said inspiratory pressures; and

curve-fitting a relationship between said inspiratory pressures and said end tidal gas concentrations.

12. The method of claim 11, wherein said gas concentrations include one or more gases exhaled by said subject.

13. The method of claim 12, wherein at least one of said gases includes carbon dioxide.

14. The method of claim 12, wherein at least one of said gases includes oxygen.

15. The method of claim 12, wherein at least one of said gases includes nitrous oxide.

16. The method of claim 12, wherein at least one of said gases includes inhaled anesthetic agent.

17. The method of claim 11, further comprising:

determining a desired inspiratory pressure for said subject based on a desired end tidal gas concentration and said relationship.

18. The method of claim 11, further comprising:

displaying said relationship; and

determining a desired inspiratory pressure for said subject based on a desired end tidal gas concentration and said display.

19. A method of setting a subject'"'"'s breath size in controlled mechanical ventilation, comprising:

varying a subject'"'"'s inspiratory pressures for a predetermined inspiratory time and predetermined expiratory time;

determining end tidal gas concentrations associated with said inspiratory pressures;

curve-fitting a first relationship between said inspiratory pressures and said end tidal gas concentrations; and

establishing a second relationship between said inspiratory pressures and tidal volumes.

20. The method 19, further comprising:

determining a desired tidal volume for said subject based on a desired end tidal gas concentration, said first relationship, and said second relationship.