Swept wavelength imaging optical interrogation system and method for using same
First Claim
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1. An interrogation system comprising:
- a tunable laser that has a tuning range wherein an optical beam is emitted therefrom which has a predetermined sequence of distinct wavelengths over a predetermined time period;
illumination optics that converts the optical beam into one or more interrogation beams which illuminate one or more biosensors;
imaging optics that collects an image from the illuminated one or more biosensors;
a 2-D imaging device that obtains a sequence of the collected images each of which corresponds with one of the distinct wavelengths of the optical beam emitted from said tunable laser; and
a data processing device that receives the collected images and processes the collected images.
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Abstract
A swept wavelength imaging optical interrogation system and a method for using the same to interrogate one or more biosensors are described herein. The swept wavelength imaging optical interrogation system is built upon a swept wavelength optical interrogation technology where a 2-D label free image is extracted from a series of high speed spectral images of the biosensor(s) without the need of performing mechanical scanning.
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Citations
22 Claims
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1. An interrogation system comprising:
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a tunable laser that has a tuning range wherein an optical beam is emitted therefrom which has a predetermined sequence of distinct wavelengths over a predetermined time period; illumination optics that converts the optical beam into one or more interrogation beams which illuminate one or more biosensors; imaging optics that collects an image from the illuminated one or more biosensors; a 2-D imaging device that obtains a sequence of the collected images each of which corresponds with one of the distinct wavelengths of the optical beam emitted from said tunable laser; and a data processing device that receives the collected images and processes the collected images. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method for interrogating one or more biosensors, said method comprising the steps of:
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emitting an optical beam which has a predetermined sequence of distinct wavelengths over a predetermined time period; converting the optical beam into one or more interrogation beams which illuminate one or more biosensors; collecting an image from the illuminated one or more biosensors; obtaining a sequence of the collected images each of which corresponds with one of the distinct wavelengths of the emitted optical beam; and processing the collected images. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22)
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Specification